Postdoctoral Fellow in Structural Biology in Mucin Domains

Göteborgs universitet / Biologjobb / Göteborg
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The University of Gothenburg tackles society's challenges with diverse knowledge. 47 500 students and 6 400 employees make the university a large and inspiring place to work and study. Strong research and attractive study programmes attract scientists and students from around the world. With new knowledge and new perspectives, the University contributes to a better future.

The Institute of Biomedicine is involved in both research and education. In both of these areas, we focus on fundamental knowledge of the living cell - what it consists of, how it works, how its function is directed by the genetic material, and how it interacts with various kinds of micro-organisms. Using this knowledge, we try to elucidate the causes of diseases, and find new ways to diagnose and treat them.

The Institute is composed of the following five departments:

• The Department of Infectious Diseases
• The Department of Microbiology and Immunology
• The Department of Pathology and Genetics
• The Department of Clinical Chemistry and Transfusion Medicine
• The Department of Medical Biochemistry and Cell Biology

At present, the institute has about 350 employees and approximately 290 million SEK in total assets.

Sahlgrenska Academy, Institute of Biomedicine, Department Medical Biochemistry and Cell Biology, Mucin Biology Groups is recruiting a post-doctoral. Service is full-time 2 years. The laboratory uses English as the main language of communication and proficient in spoken and written English is essential. The research group currently comprises about 30 researchers with some 30 additional in collaborative groups, see also www.medkem.gu.se/mucinbiology/

Subject area
Structural Biology in Mucin Domains

Subject area description
Colon and the small intestine are lined by mucus layer that protects epithelial cells from contact with the bacteria. These mucus layers are different in different parts of the intestine and failing associated with inflammatory bowel disease. The main constituents of mucus are produced by goblet cells. The airways are also protected by mucus and in this case also formed from special glands. There are a total of four different gel-forming mucins and these all have both similarities and differences. The basis of the project is now to study the molecular domains of these mucins to understand how the different parts interact and how these contribute to the different properties of the mucus.

Job assignments
Own research under guidance as for a post-doc. The work is to independently carry out projects that address how the different domains of the gel-forming mucins structure by using different types of structural biology and biochemical methods.

Eligibility
An achieved doctoral degree is compulsory for a position as postdoctor at Göteborg University. The doctoral thesis shall be in a relevant area according to the specific position stated here. Since a position as postdoctor aims to give new holders of the doctorate the opportunity mainly to strengthen and develop their scholarly proficiency, we aim for those who have a doctoral degree not older than 3 years counting from last date of application.

The qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Assessment
Holder of a doctorate in biochemistry or similar with great experience in protein structure. Particular emphasis is placed on the ability to independently express, set up and clean up various sub-domains of these mucins and then study the biochemical methods (gel filtration, electrophoresis), thermophoresis, and other methods. Competence in low-angle X-ray scattering is of special importance allowing analysis of molecular size and shape. Collaboration with other researchers doing structural analysis with NMR and electron microscopy are important. Special emphasis is also placed on the ability to independently analyze the results obtained and the use of various types of modeling programs. It is of special important to be able to work with others and to work independently.

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment
The employment is full time and temporary, two years, with placement at the Institute of Biomedicine. First day of employment as agreed.



For further information:
Please contact Professor Gunnar C Hansson, phone: +46 31 786 3488, +46 709 490005, e-mail: gunnar.hansson@medkem.gu.se

Unions
Union representatives at the University of Gothenburg: http://www.gu.se/english/about_the_university/job-opportunities/union-representatives

How to apply
In order to apply for a position at the University of Gothenburg, you have to register an account in our online recruitment system. It is the responsibility of the applicant to ensure that the application is complete in accordance with the instructions in the job advertisement, and that it is submitted before the deadline. The selection of candidates is made on the basis of the qualifications registered in the application.

The application should contain:

• A cover letter giving a brief description of previous research experience, and a motivation to why you are applying
• A CV including a list of publications
• Proof of completed PhD
• Contact details of two references

The University of Gothenburg promotes equal opportunities, equality and diversity.

Salary is determined on an individual basis.

Applications will be destroyed or returned (upon request) two years after the decision of employment has become final. Applications from the employed and from those who appeal the decision will not be returned.



In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.

Varaktighet, arbetstid
The employment is temporary, two years. Full time

Publiceringsdatum
2019-05-31

Ersättning
Salary is determined on an individual basis.

Så ansöker du
Sista dag att ansöka är 2019-06-21
Klicka på denna länk för att göra din ansökan

Företag
Göteborgs universitet

Adress
Göteborgs universitet
Box 440
40530 Gothenburg, Sweden

Kontorsadress
Medicinaregatan 9A

Jobbnummer
4832441

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