Postdoctoral Fellow in Amperometric Biosensing and Synaptic Dysfunction
Chalmers Tekniska Högskola AB / Högskolejobb / Göteborg
2025-06-23
Visa alla högskolejobb i Göteborg,
Mölndal,
Partille,
Kungälv,
Lerum eller i
hela Sverige Visa alla jobb hos Chalmers Tekniska Högskola AB i Göteborg At Chalmers University of Technology, we are committed to developing innovative technologies and methods that address some of today's most pressing societal challenges. One of the most critical global issues is health, as millions of people continue to suffer from diseases and chronic conditions.
At our university, more than 200 scientists are actively engaged in research aimed at tackling a wide range of health-related challenges-from fundamental biomedical questions to translational technologies. This postdoctoral project is an integral part of that mission, contributing to the understanding of neurodegenerative disease mechanisms.
Project overview
We are seeking a qualified postdoctoral researcher to join a collaborative and interdisciplinary project investigating the mechanisms behind synaptic dysfunction in neurodegenerative diseases. The position is part of a joint effort between multiple departments at our university and combines advanced biosensor technology, novel model systems, biophysical research on protein aggregation, and state-of-the-art imaging techniques. We anticipate this postdoctoral fellowship will contribute to impactful research in the field of neurodegeneration.
The project focuses on how toxic protein aggregates impair synaptic transmission. This will be studied using amperometric nanotip biosensors fabricated in our lab. You will also take part in developing new model systems to examine how protein aggregation affects vesicular neurotransmission.
The project involves close collaboration with a partnering lab, particularly with a postdoctoral researcher specializing in protein chemistry and advanced imaging.
Main responsibilities
• Fabrication and characterization of enzyme-based nanotip biosensors
• Culturing differentiated neuronal cells in vitro
• Performing synaptic amperometric measurements to assess neurotransmitter release in cells exposed to toxic protein aggregates
• Collaborating with project partners to develop in vitro model systems for synaptic transmission and study the impact of protein aggregation
About the division
The Division of Chemistry and Biochemistry consists of approximately 100 researchers, including PhD students and postdocs. Research at the division spans physical chemistry, organic chemistry, nanotechnology, and analytical chemistry.
This project specifically involves the fabrication of nanostructured enzyme-based electrochemical biosensors, which are used to study neurochemical activity at individual neuronal synapses and to develop advanced synaptic model systems.
Qualifications
Required:
• A PhD degree (awarded no more than three years before the application deadline*) within Neuroscience or Chemistry, preferentially with research experience in neurochemistry and electrochemistry.
• Experience with ultrafast amperometric recordings (in the kHz range) to study single-cell exocytosis
• Strong verbal and written communication skills in English.
Desirable:
• Prior research in biosensor fabrication
• Background in neurodegenerative disease research
• The date shown in your doctoral degree certificate is the date we use, as this is the date you have met all requirements for the doctoral degree. Exceptions from the 3-year limit can be made for longer periods resulting from parental leave, sick leave or military service.
Contract terms
This postdoc position is a full-time temporary employment for two years.
What we offer
Chalmers provides a cultivating and inspiring working environment in the coastal city of Gothenburg.
Read more about working at Chalmers and our benefits for employees.
Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.
Application procedure
The application should be written in English and be attached as PDF-files, as below. Maximum size for each file is 40 MB. Please note that the system does not support Zip files.
CV: (Please name the document as: CV, Surname) including:
• CV, include complete list of publications
• Previous teaching and pedagogical experiences
Personal letter: (Please name the document as: Personal letter, Family name)
1-3 pages where you:
• Introduce yourself
• Describe your previous research fields and main research results
• Describe your future goals and future research focus
Other documents:
• Attested copies of completed education, grades and other certificates.
Use the button at the foot of the page to reach the application form.
Please note: The applicant is responsible for ensuring that the application is complete. Incomplete applications and applications sent by email will not be considered.
Application deadline: 23 July, 2025
For questions, please contact:
Professor Ann-Sofie Cans, Division of Chemistry and Biochemistry
E-mail:
cans@chalmers.sePhone: 031-7726123
• ** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. ***
Chalmers University of Technology in Gothenburg conducts research and education in technology and natural sciences at a high international level. The university has 3100 employees and 10,000 students, and offers education in engineering, science, shipping and architecture. With scientific excellence as a basis, Chalmers promotes knowledge and technical solutions for a sustainable world. Through global commitment and entrepreneurship, we foster an innovative spirit, in close collaboration with wider society.
Chalmers was founded in 1829 and has the same motto today as it did then: Avancez - forward.
Ersättning enligt kollektivavtal
Så ansöker du Sista dag att ansöka är 2025-07-23
Klicka på denna länk för att göra din ansökan Omfattning Detta är ett heltidsjobb.
Arbetsgivare Chalmers Tekniska Högskola AB (org.nr 556479-5598)
Jobbnummer 9399660