Postdoc Position, Mölndal, Se, (ref Postdoc30)

AstraZeneca Mölndal / Biologjobb / Mölndal
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Postdoctoral Position:Site and mechanism of action of a family of peptide and non-peptide agonists affecting metabolic and autonomic function

Business Area Research and Development, Specialism Innovative Medicines
Department Cardiovascular and Gastroinstestinal iMed, Location Sweden (Molndal)
Closing date for applications 29 April 2013

At AstraZeneca, we're constantly striving to make new discoveries. Discoveries that will make a meaningful difference to health globally. We already have an exceptional product pipeline, and everyone here has a part to play in making sure that pipeline fulfils its potential. This is your opportunity to join them - and to fulfil your own.

We have an exciting opportunity for you to embark on a research project that aims to explore the site and mechanism of action of a family of peptide receptor ligands that control metabolic, cardiovascular and other autonomic functions. Specifically, the chief objective is to acquire data that help explain where and how the ligands act to improve cardiometabolic status, as well as how they produce mechanism-related side effects, in diabetes and obesity. The current state of knowledge in this field is conflicting and the project will involve a novel set of experimental approaches that will allow firm conclusions to be drawn. While the current project will be limited to one group of selective ligands, the findings will be generally applicable to other targets and will therefore serve as a strong basis for further career pursuit. Most parts of the project will utilize in vivo methodology which will require well developed experimental and surgical skills. The appointee will interact with experts from several disciplines and acquire insights into mechanistic drug research.

Accountabilities/Responsibilities
To assess site and mode of action of drugs, you will:
Learn, validate and apply advanced surgical lesioning methods
Set up, validate and apply chemical lesions
Apply focal CNS drug injections
Evaluate the effect of these interventions on metabolic, cardiovascular, gastrointestinal and urogenital functions

Interact and collaborate with scientists across internal functions as well as with external experts
Publish scientific papers and attend conferences to communicate novel findings to the research community
Receive advanced training to enhance professional skills and research independence; acquire in-depth understanding of the basic research and drug discovery fields to enable successful future career pursuit

Minimum Requirements - Education and Experience
A PhD in one of the following areas:
Metabolic disease (diabetes, obesity)
Integrative physiology/pharmacology

Skills & Capabilities
Solid experience in in vivo studies
Good surgical skills
Strong insight into the principles of integrative physiology and pharmacology
Ability to independently design, execute and critically interpret studies
Strong written and oral communication skills
Collaborative and interactive personality

As one of the world's leading pharmaceutical companies, our business is focused on providing innovative, effective medicines that make a real difference in important areas of healthcare. What's more, we support and encourage our people in discovering their own potential...
To read more and to apply for this position - please use this link:
http://gs.globalsuccessor.com/fe/tpl_astrazenecaV2.asp?newms=se

Publiceringsdatum
2013-03-25

Arbetstider och omfattning
Visstidsanställning 6 månader eller längre
Heltid

Ersättning
Fast lön

Så ansöker du
Sista dag att ansöka är 2013-04-29
Ange följande referens när du ansöker: POSTDOC30
Ansökan kan tyvärr inte göras via e-post.

Företag
AstraZeneca Mölndal

Adress
AstraZeneca Mölndal
43183 MÖLNDAL

Kontorsadress
PEPPAREDSLEDEN 1
MÖLNDAL

Övriga kontaktuppgifter
Telefonnummer: 031-7761000

Jobbnummer
1503547

Observera att sista ansökningsdag har passerat.

Postdoc Position, Mölndal, Se, (ref Postdoc30)

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