Postdoc position in Surface Sensitive Biological Imaging

Chalmers Tekniska Högskola AB / Högskolejobb / Göteborg
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We are looking for one postdoc to join our team in the field of surface sensitive microscopy for investigations of nanoparticle-assisted RNA drug delivery and medical diagnostics. You will be working in a stimulating research environment in the Nano and Biophysics division, performing research independently as well as part of the collaborative research centre FoRmulaEx involving academia and Swedish industry. Your research will apply and further develop surface sensitive microscopy modalities to characterize RNA-containing nanoparticles and extracellular vesicles and their interaction with biological interfaces. By increasing the understanding about the physicochemical mechanisms that promote the interaction and RNA esacpe, the hope is to improve the performance of clinically relevant delivery vehicles.

Project description
As a postdoc you will conduct own research, independently as well as in collaboration with others. Your research will focus on characterization of mRNA-containing lipid nanoparticles and further development of the surface analytical tools used to study these phenomena, in particular lable-free surface-sensitive microscopy. You will also contribute to the development of sophisticated machine-learning assisted image analysis and the design of theoretical models used for biological nanoparticle analytics. As a postdoc, you may also have the opportunity to supervise students, get experience from project management, and engage in own professional and academic development, including, if conditions permit, our teaching activities.

Information about the division and the department
The division of Nano and Biophysics at Chalmers is focused on method development of surface analytical tools designed to provide detailed information about intermolecular biomolecular interactions, with a special focus of biomolucular interactions with cellular membranes. You will work in the group headed by Fredrik Höök, which focuses on using surface sensitive microscopy to study interactions between biological nanopartiles (viruses, extracellular vesicles and lipid nanoparticles) and cell-membrane mimics. You will also be an active part of the FoRmulaEx research center - a needs-driven and interdisciplinary Swedish initiative to improve the delivery efficacy of RNA-based therapeutics through collaboration between academia and industry. We address the mRNA delivery challenge, focusing on lipid nanoparticle (LNP technology) inspired by the function of exosomes and viruses.

Major responsibilities
Your major responsibility as postdoc is to perform your own research in a research group. The position will also include collaboration within academia, industry and with society at large. The position may also involve teaching on master's levels as well as supervising master's and/or PhD students to a certain extent. The position is meritorious for future research duties within academia as well as industry/the public sector.

Qualifications
To qualify for the position of postdoc, you must hold a doctoral degree in the field of biophysics, alternatively nanoscience with clear biophysics research focus, awarded no more than three years prior to the application deadline (according to the current agreement with the Swedish Agency for Government Employers).
Expertise in optical microscopy method development, lipid self assembly and/or surface modifications is valuable competence, and you should be interested in interdisciplinary research and drug delivery.
You must have experience or willingness to learn quantitative image analysis.
You are a self-motivated and curious person with a positive and cooperative mind-set, and should enjoy to work both independently and in collaborative teams.
Your verbal and written communication skills in English are very good.
You have experience of academic publication and presentation, and have published at least one paper as first author.

Experience in one or several of the areas of lipid self assembly, single molecule micrscopy, surface modification and analysis, nanoparticle characterisation and protein is meritorious.

Contract terms
This postdoc position is a full-time temporary employment for two/three years.

We offer
Chalmers offers a cultivating and inspiring working environment in the coastal city of Gothenburg.
Read more about working at Chalmers and our benefits for employees.

Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.

Application procedure
The application should be marked with 20240029 and written in English. The application should be sent electronically and be attached as PDF-files, as below. Maximum size for each file is 40 MB. Please note that the system does not support Zip files.

CV: (Please name the document as: CV, Surname, Ref. number) including:
• CV, include complete list of publications
• Previous teaching and pedagogical experiences
• Two references that we can contact.

Personal letter: (Please name the document as: Personal letter, Family name, Ref. number)
1-3 pages where you:
• Introduce yourself
• Describe your previous research fields and main research results
• Describe your future goals and future research focus

Other documents:
• Attested copies of completed education, grades and other certificates.

Use the button at the foot of the page to reach the application form.

Application deadline: February 24, 2024


For questions, please contact:
Professor Fredrik Höök
Email: fredrik.hook@chalmers.se

• ** Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position. ***

Ersättning
Lön enligt överenskommelse

Så ansöker du
Sista dag att ansöka är 2024-02-24
Klicka på denna länk för att göra din ansökan

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Chalmers Tekniska Högskola AB (org.nr 556479-5598)

Jobbnummer
8419011

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