Post Doctoral Opportunity - Ref Nr Postdoc106
AstraZeneca Mölndal / Biologjobb / Mölndal
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Ubiquitination of the TAM receptor tyrosine kinase, AXL, and the impact on dendritic cells maturation and immune function
We're currently looking for talented scientists to join our innovative academic-style postdoc programme which spans a wide range of disciplines and aligns with one of our therapeutic areas. From our centre in Mölndal Sweden, you'll be in a global pharmaceutical environment, working alongside our scientists who are contributing to drug discovery and development and be part of a much larger active global post doc community. You will be encouraged to pursue your own independent research in cutting edge laboratories, present at external meetings, and publish in leading journals. You will also be offered a comprehensive training programme.
What's more, you'll have the support of a leading academic advisor, who'll provide you with the guidance and knowledge you need ensure success of your projects and to help develop your career. This is an exciting opportunity, to work within a Pharmaceutical setting but maintaining a strong basic science focus aligned to drug discovery and development activities, making this an opportunity to make a real difference to the future of medical science.
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialisation of prescription medicines for some of the world?s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energised and rewarded for their ideas and creativity.
You will evaluate an emerging and exciting concept that ubiquitination can modulate signal transduction of receptor tyrosine kinases. Your work will focus on the TAM receptor tyrosine kinase, AXL, and the impact of ubiquitination on the maturation and function of dendritic cells. You'll also be able to investigate E3 ligases, de-ubiquitinating enzymes and other AXL binding partners in this process. Your data will enhance our understanding of the breech of tolerance that leads to autoimmunity and chronic inflammation, and raise the role of post-translational modification enzymes? importance in drug research.
As a Postdoctoral Scientist - Ubiquitination and Immune Cell Function, it's essential that you have:A Ph.D. in Biochemistry or Cell/Molecular Biology
Proven expertise with advanced molecular biology techniques in primary mammalian cells
Evidence of independently generating creative solutions, to address research projects
A proven record of work, published in reputable scientific journals
Experience of ubiquitination and other post-translational modification techniques
Experience in site-directed mutagenesis and transfection
The following skills and qualifications are desirable:
To READ FULL JOBDESCRIPTION and TO APPLY:
http://jobs.astrazeneca.com/jobs/details/l1rPOST%20DOC%20106-post-doctoral-opportunity-respiratory-inflamation-ria-molndal-swedenPubliceringsdatum2015-03-11Arbetstider och omfattningVisstidsanställning 6 månader eller längre
Heltid
ErsättningFast månads- vecko- eller timlön
Så ansöker duSista dag att ansöka är 2015-03-28
Ange följande referens när du ansöker: POSTDOC106
FöretagAstraZeneca Mölndal
AdressAstraZeneca Mölndal
43183 MÖLNDAL
KontorsadressPEPPAREDSLEDEN 1
MÖLNDAL
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Övriga kontaktuppgifterTelefonnummer: 031-7761000
Jobbnummer 2199788
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