Post Doctoral Opportunity - Drug metabolising

AstraZeneca Göteborg / Biologjobb / Mölndal
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Regulation of drug metabolising enzymes in NASH - Cardiovascular and Metabolic Diseases

Unravelling the regulation of drug metabolising enzymes in a human in vitro liver NonAlcoholic SteatoHepatitis (NASH) model

As a Postdoctoral Scientist in the Regulation of drug metabolising enzymes in NASH, it?s essential that you have:
A PhD in cell and molecular biology and/or bioengineering
Expertise in working with primary mammalian cells
Proven expertise with advanced molecular biology techniques and strong organisational, communication and interpersonal skills
A proven record of work, published in reputable scientific journals
Evidence of independently generating creative solutions and an interest in pharmaceutical research
The following skills and qualifications are desirable:
A basic understanding of the liver steatosis/NASH disease area
Familiarity with drug metabolism and disposition
Experience of 3D cell culturing
Knowledge of bioinformatics and mass spectrometry
As a Postdoctoral Scientist in the Regulation of drug metabolising enzymes in NASH you will be:
Developing and characterising in vitro co-culture cell models that mimic different stages of steatosis/NASH in 3D liver spheroid cultures under static conditions and using a microphysiological system
Evaluating the level of expression and activity of drug metabolising enzymes in the cell models under different conditions and stages of steatosis/NASH
Elucidating the role of individual cell types and inflammatory signalling affecting the regulation of drug metabolizing enzymes at different stages of steatosis/NASH...

To READ FULL JOBDESCRIPTION and TO APPLY:

http://gs.globalsuccessor.com/fe/tpl_astrazenecav2.asp?newms=jj&id=64479&----JOB-PREVIEW-MODE----

Varaktighet, arbetstid
Visstidsanställning 6 månader eller längre
Heltid

Publiceringsdatum
2016-03-18

Ersättning
Fast månads- vecko- eller timlön

Så ansöker du
Sista dag att ansöka är 2016-04-08
Ange följande referens när du ansöker: POSTDOC129

Företag
AstraZeneca Göteborg

Adress
AstraZeneca Göteborg
43183 MÖLNDAL

Kontorsadress
PEPPAREDSLEDEN 1
MÖLNDAL

Övriga kontaktuppgifter
Telefonnummer: 031-7761000

Jobbnummer
2733171

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