PhD student in Molecular Genetics

Sveriges lantbruksuniversitet / Biologjobb / Uppsala
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Swedish University of Agricultural Sciences
Department of Animal Breeding and Genetics in Uppsala

1 PhD student in the research education subject: Molecular Genetics
Characterization and Molecular Evolutionary Analysis of the Equine Mhc

In this project you will use next generation sequencing (NGS) to characterize the genetic complexity and diversity of the complete Major histocompatibility complex (Mhc) region in the horse. The Mhc, ?the center of the immune universe? is a gene-dense region of crucial importance for initiating immune responses against infectious organisms and for combatting infectious diseases. It contains some of the most polymorphic genes in the mammalian genome and encodes for molecules that bind and present peptides from viruses, bacteria and parasites to T-lymphocytes and thereby trigger an adaptive immune response. A hallmark of Mhc evolution is the diversifying selection that is influenced by the interaction between host and microorganisms. The outcome of this challenging project will be invaluable for the understanding of inherited disease susceptibility in the domestic horse and for evolutionary processes in general.

Qualifications
An MSc degree or equivalent in a relevant field is required. We seek a highly motivated student with thorough education and strong interest in evolutionary genomics and population genetics. Previous experience with next generation sequencing methods, bioinformatics, computer programming and statistics is advantageous. We are looking for individuals who can work independently but also as part of a team. Candidates must be fluent in English (orally and written). Please prepare a letter of intent including descriptions of 1) your motivation for PhD studies in general and for this position in particular, 2) your education, especially in genetics, evolutionary biology, genomics, bioinformatics, computer programming, molecular biology, and statistics. The application should further include a CV, an authorized copy of your MSc degree, and the names and contact information (address, email address, and phone number) of at least two reference persons. Relevant publications (including your MSc thesis) should be enclosed. The application must be written in English.

Forms for funding or employment
Employment as PhD student 4 years
SLU is an Equal Opportunity Employer.

A person has basic eligibility for third level education if he or she has taken a second level qualification or has completed course requirements of at least 240 higher education credits, including at least 60 higher education credits at second level.
Those who met the requirements for general eligibility before July 1st, 2007, i.e. had completed a programme of higher education for at least 180 Higher education credits or the equivalent, will continue to do so until the end of 2015."

For selection among applicants, and for a complete advt: www.slu.se/ny-doktorand

Read more about the PhD education in the Handbook for postgraduate students
Read about the PhD education at SLU at www.slu.se/en/education/postgraduate-studies/

Use this APPLICATION FORM
http://epi-resurs.slu.se/Forskarutbildningsplatser/ansokningsblankett2_eng.doc

Applications, marked with ref no Dnr SLU ua 3146/2012, must have arrived at the Registrar of SLU, P.O. Box 7070, S- 750 07 Uppsala or registrator@slu.se no later than 2012-12-03.

Publiceringsdatum
2012-10-04

Arbetstider och omfattning
Visstidsanställning 6 månader eller längre
Heltid
Employment as PhD student 4 years

Ersättning
Fast lön

Så ansöker du
Ange följande referens när du ansöker: SLU ua 3146/2012
Ansökan kan skickas till e-postadress: Registrator@slu.se

Företag
Sveriges lantbruksuniversitet

Adress
Sveriges lantbruksuniversitet
Box 7070
75007 UPPSALA

Övriga kontaktuppgifter
Telefonnummer: 018-671000

Jobbnummer
1357535

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