PhD education in Medical science
Sahlgrenska akademin vid Göteborgs universitet / Apotekarjobb / Göteborg
2012-11-09
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Type of employment: Fixed-term employment, 4 years if full-time studies
Extent: 100 %
Location: Sahlgrenska Academy, Göteborg
First day of employment: As agreed
Reference number: UR 2012/622
Project title:
Cortical porosity - its regulation and association with fracture
Job assignments
Osteoporosis (bone fragility) is a large public health concern in Sweden today and causes approximately 70.000 fragility fractures yearly. The mortality the first year following hip fracture is 20% for women and 30% for men. In the elderly, most fractures occur at mainly cortical bone sites, such as the hip, humerus and forearm. Experimental studies have demonstrated that cortical porosity is a strong determinant of bone frailty but little is known of its role in predicting fractures in the elderly.
The primary aim of the proposed project is to determine if cortical porosity, measured using High Resolution peripheral Quantitative Computed Tomography, is higher in well characterized elderly fracture patients than in age matched controls. The secondary aims of the project are to increase the knowledge of the environmental regulation of cortical porosity. The association between cortical porosity and various types (with different loading) and dur ation of physical activity, dietary intake (especially intake of calcium and vitamin D), and smoking will be investigate in young and elderly subjects. Serum markers of signaling proteins and hormones (e.g. sclerostin and parathyroid hormone perceived to be involved in the skeletal response to mechanical loading) will be measured to investigate whether associations found are mediated by these markers. Increased knowledge in the regulation of cortical porosity and its ability to predict fracture could lead improved fracture prevention.
PhD positions are financed mainly through education grants during the first two years and employment as doctoral students during the last two years and pertains to a doctoral degree.
Eligibility
The general entry requirements are fulfilled if you have either 1, a second cycle degree (usually described as a masters degree) or 2, completed courses at an academic level corresponding to at least 240 education credits. At least 60 of these credits must be at second cycle level. 60 credits is equal to one year of full-time studies. You also need to fulfill the specific entry requirements which is an English language requirement; Engelska B.
Assessment
After the application deadline has passed, an initial assessment of the candidates eligibility is made at the faculty office and sent to the project supervisor for selection. The process can then take up to 6 months before a candidate is selected.
Additional information
For more information regarding PhD education at the Sahlgrenska academy visit
www.sahlgrenska.gu.se/doktorandportalenFor further information please contact
Mattias Lorentzon, Main supervisor
031-342 1000
mattias.lorentzon@medic.gu.seApplication deadline
2012-11-27
Appointment Procedure
Please apply online at the University of Gothenburg job application portal:
http://www.gu.se/omuniversitetet/aktuellt/ledigaanstallningar/Publiceringsdatum2012-11-09Arbetstider och omfattningVisstidsanställning 6 månader eller längre
Heltid
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2012-11-27
Ansökan kan tyvärr inte göras via e-post.
FöretagSahlgrenska akademin vid Göteborgs universitet
AdressSahlgrenska akademin vid Göteborgs universitet
Box 400
40530 GÖTEBORG
KontorsadressMedicinaregatan 3
Övriga kontaktuppgifterTelefonnummer: 031-7860000
Jobbnummer 1388211
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