PhD education in Medical science
Sahlgrenska akademin vid Göteborgs universitet / Apotekarjobb / Göteborg
2012-11-09
Observera att sista ansökningsdag har passerat.
➡️ Klicka här för den senare publicerade platsannonsen "PhD education in Medical science" (publicerad 2012-11-09) ⬅️
Visa alla apotekarjobb i Göteborg,
Mölndal,
Partille,
Kungälv,
Lerum eller i
hela Sverige Visa alla jobb hos Sahlgrenska akademin vid Göteborgs universitet i Göteborg PhD education in Medical science - Prevention of blood lipid retention in the vessel wall
Type of employment: Fixed-term employment, 4 years if full-time studies
Extent: 100 %
Location: Sahlgrenska Academy, Göteborg
First day of employment: As agreed
Reference number: UR 2012/626
Project title
Prevention of blood lipid retention in the vessel wall
Job assignments
The overall goal of this project is to study if a certain type of vessel wall thickening (intimal hyperplasia) is the foundation for atherosclerosis by serving as a trap for LDL-cholesterol (Low density Lipoproteins, "the bad cholesterol"). Vessel wall accumulation of LDL is believed to cause the inflammatory reaction that ultimately can lead to atherosclerosis. Intimal hyperplasia is naturally formed in several human arteries, such as the coronary arteries and the abdominal aorta. It is also formed following vascular interventions, such as bypass surgery. Independent of the origin of this thickening, vessels that form intimal hyperplasia are prone to develop atherosclerosis later on in life. However, it is not known whether this association is causative or non-causative.
In this project we will test the hypothesis that intimal hyperplasia causes atherosclerosis by increasing the vessel wall binding to LDL. Two models to study the binding of LDL-cholesterol to intimal hyperplasia have been developed - one in vitro and one in vivo model. We will also test the hypothesis that positively charged peptides can block LDL binding to intimal hyperplasia. Finally we will test the hypothesis that HDL (High Density Lipoproteins, "the good cholesterol"), functions as an endogenous competitor for LDL binding to the vessel wall.
Methods/assignments: Small animal surgery, mouse breeding, isolation of lipoproteins, protein chemistry, immunohistochemistry, molecular biology techniques.
PhD positions are financed mainly through education grants during the first two years and employment as doctoral students during the last two years and pertains to a docotral degree
Eligibility
The general entry requirements are fulfilled if you have either 1, a second cycle degree (usually described as a masters degree) or 2, completed courses at an academic level corresponding to at least 240 education credits. At least 60 of these credits must be at second cycle level. 60 credits is equal to one year of full-time studies. You also need to fulfill the specific entry requirements which is an English language requirement; Engelska B.
Assessment
After the application deadline has passed, an initial assessment of the candidates eligibility is made at the faculty office and sent to the project supervisor for selection. The process can then take up to 6 months before a candidate is selected.
Additional information
For more information regarding PhD education at the Sahlgrenska academy visit
www.sahlgrenska.gu.se/doktorandportalenFor further information please contact
Per Fogelstrand, Institute of Medicine
031-342 2210
perf@wlab.gu.seApplication deadline
2012-11-27
Appointment Procedure
Please apply online at the University of Gothenburg job application portal:
http://www.gu.se/omuniversitetet/aktuellt/ledigaanstallningar/Publiceringsdatum2012-11-09Arbetstider och omfattningVisstidsanställning 6 månader eller längre
Heltid
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2012-11-27
Ansökan kan tyvärr inte göras via e-post.
FöretagSahlgrenska akademin vid Göteborgs universitet
AdressSahlgrenska akademin vid Göteborgs universitet
Box 400
40530 GÖTEBORG
KontorsadressMedicinaregatan 3
Övriga kontaktuppgifterTelefonnummer: 031-7860000
Jobbnummer 1388207
Observera att sista ansökningsdag har passerat.