New Modalities Chemist based at Max-Planck Institute, Germany
AstraZeneca / Logistikjobb / Göteborg
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hela Sverige We now offer a unique opportunity for you with experience and skills in New Modalities chemistry and with a special interest in bridging chemistry and biology. We look for you with high ambitions and a desire to work with an open minded experienced team to push the boundaries of science in a unique setting between industry (AstraZeneca) and academia (Max-Planck Institute). You will be employed by AstraZeneca, Sweden but the position is placed at the Max-Planck Institute in Dortmund, Germany.
AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration where the employees are made to feel valued, energized and rewarded for their ideas and creativity.
The Innovative Medicines (IMED) Biotech Unit of Cardiovascular, Renal and Metabolism (CVRM) is one of AstraZeneca 's core therapy areas. We push the boundaries of science to deliver life-changing medicines to patients suffering from Heart Failure, Diabetes or Chronic Kidney Disease. To realize our ambitions we stay agnostic to molecular modality.
We drive our pipeline and the areas of scientific leadership to a large extent in collaborations with world experts which provides you as a scientist with the unique opportunity to access the most advanced knowledge and opportunities to stay at the fore-front of science. The Medicinal Chemistry Department within CVRM is a critical player in the discovery and design of our drug molecules and in identifying and validating novel biological targets.
Setting
The Senior Scientist is a senior member of the AstraZeneca Satellite Unit at the Max Planck Institute for Molecular Physiology, in Dortmund, Germany, which was established in 2015. There, AstraZeneca scientists from CVRM IMED are directly embedded in the academic environment of the group of Prof. Herbert Waldmann. Researchers from industry and from academia are working side-by-side in the same laboratories to address challenging therapeutic targets through novel strategies in the New Modalities area. More information on this collaboration:
https://www.astrazeneca.com/partnering/partnering-case-studies.htmlJob Purpose
The objective of the Satellite Unit team is focused on demonstrating scientific leadership and generating novel ideas and strategies for challenging biological targets, which may then be taken into the AstraZeneca portfolio.
The Senior Scientist will demonstrate expertise in the area of New Modalities Medicinal Chemistry (e.g. peptides, macrocyles, PROTACs, RNA etc). The Senior Scientist will actively contribute to project strategies, compound design and synthesis, data generation and data interpretation in projects at the MPI Satellite unit as well as in AZ portfolio projects. This requires an active collaboration not only with the project team at the MPI and but also with the New Modalities chemistry team at AstraZeneca Gothenburg.
The role is chemistry centric but will include application of chemical biology techniques in collaboration with the experts at the MPI.
Key success factors for role
* Expert knowledge of synthetic chemistry related to at least one area of New Modalities such as peptides, macrocycles, PROTACs or oligonucleotides.
* Willingness to generate data using a wide set of chemical biology and biochemistry techniques
* Ability to design and execute experiments autonomously and show creativity in solving wide range of scientific challenges
* High quality and consistent delivery from own work
* Excellent teamwork, collaboration and communication within team and across both Prof. Herbert Waldmanns team at the MPI and AstraZeneca CVRM chemistry teams in Gothenburg.
* Excellent awareness of current developments in New Modalities
* Publishing in peer reviewed journals or present at internal/external conferences.
Minimum requirements
* Ph. D. degree or corresponding experience in Organic Chemistry, Medicinal Chemistry or Chemical Biology related to New Modalities. 2+-year post-doctoral experience in academic or industrial setting preferred
* Synthetic chemistry related to New Modalities; ability to plan, prioritise and perform work independently including retro-synthesis and route design
* Scientific Creativity, including the ability to identify, develop and apply new technologies and ways of working within New Modalities chemistry.
* Will be a highly self-motivated, scientifically critical individual capable of receiving and analyzing input from complex data and deciding on focused course of action.
* Excellent awareness of recent literature within field of expertise
* Excellent written and verbal communication skills, including presentation to senior Chemistry leaders, and clearly written documents and scientific papers.
* Strong ability to work collaboratively and build relationships
* Prior experience in Chemical Biology and/or Drug Discovery is seen as an advantage.
If you are interested, apply now!
Please apply as soon as possible, as we are constiniously screening and interviewing candidates.
For more information please contact Dr. Eric Valeur, Eric
AstraZeneca is an equal opportunity employer and will will consider all qualified applicants for employment without discrimination.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-06-08ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-07-06
Ange följande referens när du ansöker: R-022134
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
ulrica.marklund1@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparedsleden 1
Jobbnummer 4193890
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