Job Description Clinical Pharmacometrician in Respiratory & Imm
AstraZeneca AB / Biomedicinjobb / Mölndal
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Do you have experience and expertise in mathematical modelling and simulation, PKPD and its application in drug development? Do you also share our passion to explore possibilities of science to change lives? If yes, your next challenge might be this role at AstraZeneca!
This is an opportunity for a talented and engaged individual to join our growing Clinical Pharmacology and Quantitative Pharmacology team and develop as a Clinical Pharmacometrician supporting large and small molecule projects across full development within the therapy area of Respiratory & Immunology.
AstraZeneca is a world-leading pharmaceutical company, we focus on discovering and developing medicines that make a real difference to millions of patients. Within the Clinical Pharmacology and Safety Sciences (CPSS) function, we have a state-of-the-art quantitative clinical pharmacology group with a diverse and uniquely skilled team of clinical pharmacometricians and clinical pharmacology scientists.
Thrive in an energizing environment where challenging work goes hand in hand with development. With opportunities, recognition and bright minds, there's no better place to unlock learning and build a long-term career.
What you'll do:
You will work closely with clinical pharmacology scientists, physicians and other scientists and apply modelling to support the design and interpretation of clinical studies and influence key decisions in early and late clinical development.
The work includes integration of relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. Supporting informative trial designs using simulations and efficient modelling statistics is an important focus area for us. In collaboration with clinical pharmacology scientists, you'll represent Clinical Pharmacology and Quantitative Pharmacology and be responsible for identifying and executing modelling to support model informed drug development. You will communicate your findings to other scientists within and outside of AstraZeneca and publish them in peer reviewed journals.
Requirements:
PhD or equivalent (M.Sc/Pharm.D.) level expertise in quantitative modelling , e.g. knowledge in mathematics and statistics applied to life sciences
Working knowledge of pharmacokinetics and its clinical application
Background and an understanding of clinical pharmacology aspects of drug development, preferably in both the small and large molecule setting
Experience with PK/PD analysis and statistical (pharmacometric) tools such as Phoenix Winnonlin, Nonmem, R
Biological understanding of disease and drug action
Good oral and written communication skills
Desirable for the role:
Recognized scientific expertise demonstrated by scientific publishing in the field of clinical pharmacology
Early or late phase clinical development experience/awareness.
Why AstraZeneca?
We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide. It drives us to work together as one global team to achieve our goals. A supportive place where all are encouraged and achievement is recognised. Strengthening our knowledge through constructive feedback and coaching, as well as collaborating with the best.
If this sounds like the job and workplace for you - apply today!
Publiceringsdatum2022-07-05Så ansöker duSista dag att ansöka är 2022-07-15
AdressAstrazeneca AB
PEPPAREDSLEDEN 1
43183 MÖLNDAL
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-135733".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Pepparedsleden 1 (
visa karta)
431 83 MÖLNDAL
Ansökan E-post:
ulrica.marklund1@astrazeneca.com Arbetsplats AstraZeneca Göteborg
Jobbnummer 6801798
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