Head Of Dmpk Design Leaders (ddl) And Biotransformation
AstraZeneca AB / Kemistjobb / Göteborg
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hela Sverige AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. At AstraZeneca, we're proud to have an inspiring workplace culture that encourages innovation and collaboration. Here, employees are empowered to express diverse perspectives and are made to feel valued, energized and rewarded for their ideas and creativity. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you're our kind of person.
We are now hiring a Head of DMPK Design Leaders (DDL) and Biotransformation, within department of Drug Metabolism and Pharmacokinetics (DMPK) and the Early Respiratory, Inflammation and Autoimmunity therapy area. The position is placed at AstraZeneca's vibrant R&D site in Gothenburg, Sweden, one of AstraZeneca's three strategic science centers.
This is a scientific and strategic role accountable for leading a team of up to six scientists, all delivering into multidisciplinary project teams. You are expected to have insight of how the chemical properties of the drug link to pharmacokinetic and pharmacodynamic properties and ultimately predictions of efficacious dosing. You will be part of Early RIA DMPK leadership team, where you will oversee and implement best-practice and process for DMPK project work as well as lead the DMPK functional review of the Early RIA portfolio. You are also expected to operate as DDL at times.
Main Responsibilities:
* Act as a line manager, ensuring a fair distribution of work amongst the team and see to that the team/section is constantly advancing through appropriate personal and team objectives.
* You will work through personal objective setting and ensure high performance of team members.
* Make your team a great place to work through provisioning of individualized development opportunities and by role-modelling respectful and inclusive behavior.
* As a member of Early RIA DMPK Leadership Team you are requested to be pro-active in anticipating the changing needs of the department, come up with new ideas, make proposals to keep the department active and scientifically forward-thinking.
* Be up to date with the scientific literature relevant to drug design work (PK, DMPK, PhysChem, Biotransformation) and use this to influence the science performed in RIA.
* Seek internal and external collaborators who share a passion for science to seize opportunities for advancing DMPK science, increasing the speed and probability of success for drug discovery projects.Take on DDL responsibility when required, including following tasks:
* Analyse DMPK experimental data in relation to chemical structure and have a high-level knowledge and skill in pharmacokinetics and relation of PK parameters to drug property space.
* Apply an expert understanding of DMPK, physico-chemical property assays and biotransformation reactions to support/influence compound design and project progression.
* Be present in the DMPK laboratory, designing and conducting appropriate experimental studies.
Essential Requirements
* You have a scientific background with strong interpersonal skills. In addition, an ability to engage and collaborate across boundaries with a problem-solving attitude and with focus on delivery.
* We believe that you possess basic PK modelling skills, understanding of disease biology and translational PK/PD. Furthermore, you master complex DMPK matters, and can link these to the impact on safety and efficacy.
* Ph.D. in chemistry, pharmacy or related with a minimum of 5 years of experience in a drug discovery DMPK department within a pharmaceutical company, or equivalent experience.
* Scientific in-depth knowledge in the DMPK field
* Excellent written and verbal communication skills in English
* Knowledge of the pharmaceutical drug discovery and development process
* Strong influencing, networking and leadership skills
* Experience from biotransformation in drug discovery and development setting including regulatory requirements.
*
For more information about these positions please contact hiring manager Markus Fridén at markus.friden(@)astrazeneca.com
Welcome with your application no later than 2019-12-08.
Additional information
Our Gothenburg site:
https://www.astrazeneca.com/our-science/gothenburg.htmlCulture and atmosphere of the Gothenburg site:
https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/Life in Gothenburg and Sweden:
https://www.movetogothenburg.com/AstraZeneca is acting as an Employment Agency in relation to this vacancy.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2019-11-18ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2019-12-09
Klicka på denna länk för att göra din ansökanFöretagAstrazeneca AB
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-066124".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Jobbnummer 4961957
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