Early Research Scientist
Qrios Minds AB / Kemistjobb / Solna
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hela Sverige QRIOS Life Science is recruiting a new consultant, a scientist specializing in proteins and biologics, to join the section of Early Discovery & Research at Chiesi, an international research-focused pharmaceutical company.
Would you like to play an essential role in evolving early discovery projects within rare diseases by working hands-on in the laboratory. This might be the perfect opportunity for you! Welcome with your application!
About the position
Chiesi is an international, research-focused family-owned pharmaceutical company that has established a strong heritage in developing innovative pharmaceutical solutions to improve the life of patients with high unmet medical needs.
In this role, you will be a part of the Candidate Development&Characterization group in Chiesi Global Rare Diseases (GRD) and join a great team with competent and dedicated colleagues working with discovery and research projects within rare diseases.
The main research focus is lysosomal storage disorders and how to bring biologics into the CNS. You will report to the manager of the group GRD, R&D and will work together with the GRD R&D team and be allocated to multinational project teams.
This is a long consultant assignment where you will be hired by QRIOS Life Science and work on-site at Chiesi, based at KI Campus Solna/Stockholm.
Responsibilities
To participate in drug candidate development by designing experiments and perform laboratory work - examples of work areas:
• Develop and establish relevant enzymatic assays.
• Determine catalytic activity and protein concentration in in-process samples and final product from production of drug candidates to develop the production strategies together with the production team.
• Sample and buffer preparation for biophysical characterization of glycosylated candidates which may include: SDS PAGE, IEF, western blotting, labelling, enzymatic cleavage development.
• Buffer preparation for production.
Your profile
The right candidate has a BSc or MSc in relevant scientific discipline with a couple of years of experience in the field. You have documented experience from the biopharmaceutical industry or from academia, with specific focus on proteins and biologics.
Experiences sought for:
• Knowledge in general biochemistry and analytical method development.
• Hands on experience of analysis of biologics:
- Enzymatic activity methods
- Protein concentration measurements
- Sample preparation techniques
- SDS PAGE and western blotting
- Buffer preparation
It is meritorious if you have:
• Experience of setting up Design of Experiments (DoE)
• Experience from CNS research and rare diseases is an advantage.
• Hands on experience of:
- HPLC
- Protein purification
- Sterile techniques and mammalian cell culture
- Endotoxin measurements
- Binding assays such as ELISA and receptor binding assays
- Thermostability
- Labelling and tagging strategies for proteins
To be successful in this role you have a genuine scientific interest, strong interpersonal skills and you are used to work in a "collaborative mode" in multi-disciplinary and multi-nationally project teams. You have good communication skills and the ability to share your results, experiences and knowledge in meetings with internal and external partners.
You are analytical, organized, and thorough and it is important that you are results driven and enjoy working in a fast-paced environment. Being able to handle multiple tasks independently and manage priorities in order to meet project timelines are important skill sets for this position. Fluent English both speaking and in writing is required.
About the organisation
About Chiesi - A GLOBAL FAMILY DEDICATED TO PEOPLE AND PATIENTS
In Chiesi our approach as a Benefit Corporation is a way of being as well as a way of thinking. We redefine the way to do our business, to create a positive impact on people, environment and our global Chiesi Community, acting as a force for good.
We are passionate and committed to improving and raising the quality of human life and making meaningful contributions that will have a positive long lasting impact. Our entrepreneurial thinking, our sustainable and innovative ideas, transformative solutions and our personal chemistry are the key elements that bonds us and make us grow as one cohesive global Chiesi family.
EVERYONE OF US IS DIFFERENT, EVERYONE OF US IS CHIESI
For information about Chiesi, please visit
www.chiesi.com and for info about the Global Rare Diseases unit, please visit
www.chiesiglobalrarediseases.com. Ersättning Fast lön
Så ansöker du Sista dag att ansöka är 2024-02-04
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "986".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Qrios Minds AB (org.nr 556599-5999),
http://www.qrios.se/ Arbetsplats Qrios Life Science & Engineering AB
Kontakt Hanna Peterson
hanna.peterson@qrios.se Jobbnummer 8392990
Observera att sista ansökningsdag har passerat.