Drug delivery scientists - Bioscience
AstraZeneca AB / Biomedicinjobb / Göteborg
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hela Sverige When we at AstraZeneca see the chance to change, we take this opportunity - for every opportunity, no matter how small, can be the beginning of something big. Delivering medicine that changes people's lives is about having an entrepreneurial spirit - finding moments and understanding its potential.
Pharmaceutical Sciences at AstraZeneca deliver the therapies of the future through scientific leadership in drug delivery, design of synthetic routes, and manufacturing of Active Pharmaceutical Ingredients (API) and drug products. Our portfolio of projects spans traditional small molecules, peptides, oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas. Advanced Drug Delivery (ADD) resides within Pharmaceutical Sciences with a mission to provide novel products to AstraZeneca's clinical pipeline.
We are now looking for two enthusiastic and innovative cell biologists to work on delivering new modalities for gene therapy. One position is to be based in Cambridge, UK and one in Gothenburg, Sweden.
Together with chemists and formulation specialists, you will be responsible for engineering and testing delivery systems for nucleotides and proteins, like CRISPR components. Using automation, multivariate methods and rapid prototyping you will help improve our methods for creating new and better delivery systems. Working with scientific expertise from the UK, US and Sweden, on global drug projects, will be part of your routine. You will also be expected to drive science networks and provide high quality scientific input across the organisation. We expect you to be an active member of the external scientific community, enhancing our reputation as scientific leaders in the advanced drug delivery field.
We are seeking an ambitious scientist with a strong foundation in the delivery sciences and a specialisation in cell biology, and of course, a great passion for experimental science. This is a hands-on, lab-based position where you will work with different teams, so you should enjoy communicating and have the capacity to share your data.
If you are committed to developing your career in the pharmaceutical sciences - this might be the role for you!
Essential Requirements
* PhD or Master's degree in biology or related discipline, with extensive experience culturing and analysing different cell types
* High technical aptitude and extensive experience with instrumentation related to cell biology.
* Molecular biological and cell engineering skills, a working knowledge of CRISPR-related biology and a good knowledge of endosomal biology
* Strong record of scientific excellence evidenced by publications, patents and presentations
* Thorough understanding of principles, applications and management of Safety Health and Environment (SHE)
Desirable Requirements
* Practical experience working with in vivo mouse models is highly desirable
* Experience with laboratory automation including fluidic handling robots and automated analytical systems (robotic microscopy and image cytometry, flow cytometry, sequencing and/or mass spectrometry)
* A good understanding of software for handling large multivariate datasets
* 3D culture work or, work with microphysiological systems
* Experience working with nanomedicines and experience formulating intracellular delivery systems for nucleotides and/or proteins
* Experience with supervision and/or training of colleagues
Are you already imagining yourself joining our Advanced Drug Delivery team? Good, because we can't wait to hear from you.
For more information about the positions please contact Arpan Desai, Team Leader (UK), at or Sara Richardson, Team Leader - Formulation and Bioassays (Sweden), at
We encourage you to send your application as soon as possible, but no later than January 31, 2020
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2020-01-18ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2020-01-28
Klicka på denna länk för att göra din ansökanFöretagAstrazeneca AB
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-069106".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Jobbnummer 5048543
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