Doktorand i mikroskopi
Phase Holographic Imaging Phi AB / Logistikjobb / Lund
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The purpose of this project is to develop and use a cell friendly method to identify and study sub-populations of cells within larger populations. We will study the cancer stem cell sub-population and evaluate the effect of different cancer treatments on this population compared to the entire cell population over time. For this purpose we will use digital holographic microscopy (DHM), which is a non-invasive method to study cells both momentarily and in a time lapse manner for several days. The goal will be to bring to market a new set of tools for cell biologists.
Digital holography is an emerging high-resolution imaging technique that offers real-time imaging and quantitative measurements of physiological parameters without any staining or labeling of the cells and without photo toxicity. Cells in a tissue culture vessel can be monitored for several days and cell division and cell movement of individual cells can be recorded. Cell populations are heterogeneous and in cancer cell lines a so called cancer stem cell sub-population is found. One goal of the project is to detect cancer stem cell sub-populations using digital holography alone or in combination with certain antibody labels that increase the optical density of cells. Also, an important part of the work will be to develop the combination of digital holographic microscopy and intermittent fluorescence detection of fluorochrome-labelled cells.
The applicant needs to have good technical and cell biological knowledge. Cell culture and optics are integrated parts of the project and solid knowledge in these areas is required. We prefer applicants with good references, including good grades. Personal qualities are very important, and we are looking for a project-oriented creative team-player who thrives in an innovative environment. Excellent English skills are a plus.
The position is a cooperation between PHI and the Department of Biology at Lund University. The position will comprise optic and other microscopy development, contact with international researchers and cell biology work as well as teaching at university courses in toxicology and cell culturing. It is a four year position, but teaching may prolong the duration up to five years.
You can find more information about the company on our website
www.phiab.se . The last day to submit an application is March 15th, 2014. For more information or to send in your application, please contact us at
PhDstudent@phiab.sePubliceringsdatum2014-02-25Arbetstider och omfattningVisstidsanställning 6 månader eller längre
Heltid
Tjänsten är en fyra-års utbildningsanställning med målet att doktorera
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2014-03-15
Ansökan kan skickas till e-postadress:
PhDstudent@phiab.seFöretagPHASE HOLOGRAPHIC IMAGING PHI AB
AdressPHASE HOLOGRAPHIC IMAGING PHI AB
SCHEELEVÄGEN 22
22363 LUND
KontorsadressSCHEELEVÄGEN 22
LUND
Övriga kontaktuppgifterTelefonnummer: 046-386080
E-postadress:
info@phiab.se Jobbnummer 1790010
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