Discovery Safety Specialist / Toxicologist

AstraZeneca / Apotekarjobb / Göteborg
2019-01-25
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Would you like to bring your scientific excellence to the Drug Safety and Metabolism function and become a key player in the discovery of safe innovative medicines? Would you like to apply your expertise in a company that is following the science and turns ideas into life changing medicines? Then you might be the one we are looking for!

AstraZeneca is looking to recruit a Discovery Safety Specialist / Toxicologist to strengthen the Safety Science and Discovery team within the Cardiovascular, Renal and Metabolism (CVRM) Safety department. The positions will be on an Associate Principal Scientist level and is placed at AstraZeneca's dynamic R&D site in Gothenburg, Sweden.

One of the major challenges in the discovery of innovative medicines is to ensure they are safe enough to provide novel treatments for patients. CVRM Safety department is part of our global Drug Safety and Metabolism (DSM) function. The Safety Science and Discovery teams develop and apply innovative scientific strategies to drive the design and selection of safe medicines for patients suffering from CVRM diseases. As true Drug Hunting partners, we contribute to the selection of novel drug targets, design of therapeutic concepts, identification and optimization of new chemical (and a range of other modalities) series as well as selection of novel candidate drugs. We develop and apply cutting edge molecular, cellular and in vivo technologies to push the boundaries of predictive safety science and investigative toxicology with our mission in mind:

SCIENCE, PASSION, EXPERTISE - Fundamental to selection and delivery of safe and efficacious medicines to patients

Within DSM, we put a strong emphasis on talent development. You will be able to develop your scientific leadership by working together with leaders in investigative toxicology, drug discovery, cell biology, and predictive safety science.

Main Duties and Responsibilities

* Be responsible for the safety strategy in multi-disciplinary drug discovery project teams
* Provide scientific leadership to influence project decision making with the aim to deliver molecules with the Right Safety profile.
* Design and build in vitro and in vivo strategies to predict, assess, and mitigate target and drug related safety risks as well as executing through internal and external experimental capabilities.
* Develop innovative solutions and research proposals based on strategic needs of the discovery project portfolio. Pursue cutting edge science and technologies in order to optimize and influence safety assessment of novel drugs.
* Engage with world-class experts across our organization to develop, refine and implement innovative experimental strategies and use the data to assess and/or provide mechanistic understanding of safety issues.
* Contribute to the discovery of innovative treatments for CVRM diseases.

Requirements

* Excellent scientist with a PhD or equivalent experience in toxicology, cell biology, pharmacology, systems biology or related field
* Strong scientific track record
* Experience with design of strategies and/or execution of in vitro and/or in vivo experiments to determine the safety and/or efficacy of therapeutics (e.g. small molecules, oligonucleotides, peptides, regenerative therapies, etc) is an advantage.
* Preferably >3 years' experience as safety scientist in the drug discovery phase (from project conception to candidate drug selection).
* Excellent communication, presentation and influencing skills across levels/disciplines.
* Highly motivated, creative and innovative scientist that solves problems in a goal-focused manner
* Excellent inter-personal skills that contributes to an open, positive, team oriented and collaborative working climate.

If you are interested, apply now!

For more information please contact recruiting manager Mikael Persson, Director Safety Science and Discovery at mikael.persson(at)astrazeneca.com

Welcome with your application no later than February 17, 2019.

AstraZeneca is a global, science-driven biopharmaceutical company. We turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. Here, we see the impact of our collective ideas and expertise, and the power of science to deliver them. AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2019-01-25

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2019-02-15
Ange följande referens när du ansöker: R-043734
Klicka på denna länk för att göra din ansökan

Kontakt
AstraZeneca ulrica.marklund1@astrazeneca.com

Företag
AstraZeneca

Adress
AstraZeneca
43183
43183 1480

Kontorsadress
Pepparedsleden 1

Jobbnummer
4576619

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