Design Leader Dmpk To Astrazeneca Gothenburg
Alten Sverige AB / Biomedicinjobb / Göteborg
Observera att sista ansökningsdag har passerat.
Visa alla biomedicinjobb i Göteborg,
Mölndal,
Partille,
Kungälv,
Lerum eller i
hela Sverige Visa alla jobb hos Alten Sverige AB i Göteborg,
Härryda,
Trollhättan,
Uddevalla,
Grästorp eller i
hela Sverige About AstraZeneca
AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a phenomenal workplace culture that encourages innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
We are looking for a motivated individual to take on take on the role as Drug Metabolism and Pharmacokinetic (DMPK) Design Leader (DDL) for 12 months. Alternatively, it is an opportunity for a highly talented indivudal with less specific experience to assist an experienced DDL whilst training for the role. The DDL role is a strategic and scientific role where you will work closely with Medicinal Chemistry, Bioscience and representatives from other functions in drug discovery. You will influence chemical drug design by optimizing the ADMET (absorption, distribution, metabolism, excretion, toxicity) for compounds within projects. In addition to oral drugs, the task is also to optimize inhalation properties for projects aiming for this route of administration.
The successful applicant will contribute to RIA drug design teams by providing DMPK expertise and input to the design of new compounds. This includes analysis of ADMET and efficacy data and to develop a strategy for how to improve these and subsequently influence project progression.
You are expected to have understanding of DMPK and chemistry to be able to provide advice and interpretation of complex drug discovery data.
Main Duties and Responsibilities:
• Lead DMPK-related activities and the optimisation of compounds by balancing the properties associated with absorption, distribution, clearance, elimination and lung targeting to ensure that DMPK challenges are thoroughly assessed and resolved
• Deliver DMPK input and data to projects within agreed timelines and to the right quality
• Accountable together with Medicinal Chemistry, Bioscience and Safety, for compound design and effective cross-discipline optimization and Design-Make-Test-Analysis (DMTA) cycles in drug discovery
• Apply an understanding of DMPK and physicochemical properties to support/influence compound design, project progression and project strategy
• Responsible for leading, coordinating and engaging with RIA DMPK colleagues in project related activities
• Prepare clear presentations related to the above for internal governance bodies
Requirements:
• Formal training or proven experience of working with pharmacokinetics and drug metabolism.
• PhD or equivalent experience in a relevant discipline (Medicinal, Organic or Physical Chemistry or bio-pharmaceutics/pharmacokinetics)
• Understanding of correlations between physicochemical characteristics and their influence on DMPK properties and subsequent design of new compounds.
• Experience from drug discovery cross-functional work and compound/project progression is desirable
• Ability to engage and collaborate across boundaries with a problem solving attitude and focus on delivery
What we offer you at ALTEN
Every employee is equally valuable in the success of ALTEN! We are driven by making people grow and develop, which is why we offer you the opportunity to work with what you are truly passionate about. At ALTEN, we have a broad range of assignments at most of the leading companies in Sweden in several different sectors, to make it possible for your wishes to come true. We offer both national and international opportunities and together with your coaching manager, you build your career path so you constantly are able to develop and achieve your goals and dreams!
As a consultant at ALTEN, you will get the genuine team feeling at your assignment but also a wonderful togetherness at ALTEN. Through our different internal networks, such as ALTEN Sports, Women@ALTEN and ALTEN Innovation you will get the opportunity to drive topics and activities that are close to your heart, together with your colleagues. All activities are of course optional. Work life balance is our top priority. We also have a collective agreement and other benefits like Pension, Insurances and Wellness grants.
We believe in growing together!
Please note: Between 20th December and 8th January we will not be able to answer questions and no selection will be made during this period. Merry christmas and Happy new year!
Varaktighet, arbetstid
Heltid Tillsvidareanställning
Publiceringsdatum2019-12-20ErsättningEnligt överenskommelse
Så ansöker duSista dag att ansöka är 2020-01-15
Klicka på denna länk för att göra din ansökanFöretagAlten Sverige AB
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Alten Sverige AB (org.nr 556420-7453)
Jobbnummer 5013604
Observera att sista ansökningsdag har passerat.