Computational Chemist, New Modalities
AstraZeneca / Kemistjobb / Göteborg
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hela Sverige Do you want to join a world leading team in developing the next generation of respiratory medicines?
AstraZeneca R&D, Gothenburg, Sweden seek to recruit an Associate Principal Scientist Computational Chemistry with focus on new modalities in the area of Respiratory, Inflammation & Autoimmunity (RIA).
Mission
AstraZeneca is committed to the development of the next generation of innovative respiratory medicines. The Computational Chemistry team leads efforts to expand the use of state of the art in silico methods for modelling, ligand design, property predictions and data analysis supporting the RIA drug discovery projects with a focus on small to medium sized molecules. The team operates in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Bioscience, DMPK and Pharmaceutical Sciences departments to advance the RIA project pipeline.
Job description
As a Computational Chemist you will have a profound impact on multiple projects across the RIA portfolio with a focus on target identification, lead generation and lead optimization - and with a particular focus on New Modalities such as Peptides, Macrocycles or Oligonucleotides.
You will have a key role in modelling, analysis of large datasets and drug design. You will be a significant contributor to project progression and a project team member. The role holder will also provide discipline based scientific leadership and represent the department and AstraZeneca at interdisciplinary meetings and conferences, both internally and externally.
Major Duties and Responsibilities
* The candidate will have a profound expertise in the drug design of New Modalities such as peptides, macrocycles or oligonucleotides.
* He/she will impact simultaneously multiple discovery projects by efficiently and pro-actively applying a wide variety of computer-aided drug design approaches.
* The work will include helping project teams analyze, interpret, and visualize biological data, and the communication of results within project teams and departments.
* With excellent knowledge of modern computational chemistry the candidate will identify and drive areas of scientific improvements for computational chemistry
* The candidate will be expected to plan, write and publish high quality scientific papers.
Education
We are seeking a computational chemist with a PhD (or equivalent experience) in computational chemistry, biophysics, or a related field and a strong expertise in the field of New Modalities such as peptides, macrocycles or oligonucleotides. Industry experience is a plus, but not a must. The candidate should aim at joining our fast-paced multidisciplinary RIA computational chemistry team; he/she is expected to have a high degree of independence and a track record of excellence in a number of computer-aided drug design techniques to assist in target identification and advancement of discovery programs.
Requirements and Qualifications
* Solid knowledge of computational chemistry and medicinal chemistry concepts.
* Expertise in using computational chemistry software as well as knowledge in scientific computing, and programming skills (e.g. Python, Perl, C, C++, Java).
* Strong expertise in drug design of New Modalities (e.g. peptides or oligonucleotides).
* Excellent written and verbal communication skills.
More information
For more information about this position please contact: Dr. Anders Hogner, Medicinal Chemistry, IMED RIA,
Please send your application no later than January 22th, 2018.
AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. The Respiratory, Inflammation & Autoimmunity (RIA) unit is one of AstraZeneca 's core therapy areas focused on the discovery and development of novel treatments for respiratory diseases.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-01-09ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-01-22
Ange följande referens när du ansöker: R-020251
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
asa.lothigius@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparedsleden 1
Jobbnummer 3891301
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