Computational Chemist at AstraZeneca R&D in Gothenburg

Alten Sverige AB / Apotekarjobb / Göteborg
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About AstraZeneca
AstraZeneca is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. AstraZeneca is proud to offer a unique workplace culture that inspires innovation and collaboration. Co-workers are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

Do you have expertise in Computational and Medicinal Chemistry? Would you like to join a world leading team that push the boundaries of science to deliver life-changing medicines? Then you might be the one we are looking for!

Are you an analytical chemist interested in learning more about preparative chromatography? Would you like to work in a cross-functional environment using state of the art technology? Then you might be our next member in the Separation Science Laboratory team!

We are looking for a computational chemist that can join our team for a temporary position (approximately 1.5 year, 2020-03-01) in AstraZeneca R&D, Gothenburg, Sweden.

The Computational Chemistry team use of state of the art in silico methods for modelling, ligand and structure-based design, data analysis, property predictions and data analysis supporting the Cardiovascular, Renal and Metabolic (CVRM) drug discovery projects. The team operates in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Bioscience, DMPK and Pharmaceutical Sciences departments to advance the CVRM project pipeline.

This is a compchem project support (drug hunting) position, where you are expected to impact multiple projects across the CVRM portfolio with a focus on target identification, lead generation and lead optimization including "New Modalities" such as Peptides and Macrocycles. Previous experience and if you can start immediately is an advantage.

Main Duties and Responsibilities:
• Impact simultaneously multiple discovery projects by efficiently and pro-actively applying a wide variety of computer-aided drug design approaches.
• The work will include helping project teams analyze, interpret and visualize biological data and the communication of results within project teams and departments.

Essential requirements:
We are seeking a drug hunter with a PhD (or equivalent experience) in computational chemistry, biophysics, or a related field with industry experience who would like to join our fast-pace multidisciplinary CVRM computational chemistry team. The candidate is expected to have a high degree of independence and a proven record of excellence in a number of computer-aided drug design techniques to assist in target identification and advancement of discovery programs.

• Solid knowledge of computational chemistry and medicinal chemistry concepts
• Expertise in using and improving computational chemistry software as well as knowledge in scientific computing, and programming skills (e.g. Python, Perl, C, C++, Java)
• Expertise in using chemoinformatics techniques
• Experience of non-target based strategies (e.g. phenotypic screens) and or experience of computational chemistry applied on peptides, macrocycles or nucleotides will be seen as an advantage
• Very good written and verbal communication skills

About ALTEN
For over 20 years, ALTEN has developed its business by keeping to the core values that have built up the company's success. Every year, hundreds of ALTEN consultants have been given the opportunity to embark on challenging technical projects for our customers. ALTEN has a tradition of developing products in many areas, and history in Sweden is based primarily on skills in mechanics, software and electronics. Thanks to a successful concept in which we utilize the expertise of experienced consultants and develop young abilities towards a successful career, we have gained ground in many industries. Our Pharma initiative is based on the same successful concept with the same strong structure, but in a new exciting industry and a new field of expertise that includes knowledge in chemistry, biotechnology and biomedicine.

As an employee at ALTEN, we offer you a competitive salary based on your performance and work experience. You also have the opportunity to influence your assignments, different benefits and your overall working environment as well as choose your career path. We offer a wide range of internal trainings and an opportunity to plan for an international career. It is our conviction that genuine commitment is created through choice and the ability to influence your own personal development - our business model provides that opportunity. This freedom of choice enables us to offer our clients the most committed consultants, regardless of assignments. At ALTEN, we believe in growing together!

For questions about the position, please contact Business Manager Pharma, Rickard Westergren at rickard.westergren@alten.se

Varaktighet, arbetstid
Heltid Tillsvidareanställning

Publiceringsdatum
2019-05-21

Ersättning
Enligt överenskommelse

Så ansöker du
Sista dag att ansöka är 2019-05-24
Klicka på denna länk för att göra din ansökan

Kontakt
HR-avdelningen, Alten

Företag
Alten Sverige AB

Adress
Alten Sverige AB
Theres Svenssons gata 15
41755 Göteborg

Kontorsadress
Theres Svenssons gata 15, Göteborg

Jobbnummer
4801412

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