Computational Chemist at AstraZeneca R&D, Gothenburg
AstraZeneca AB / Kemistjobb / Göteborg
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hela Sverige Do you have expertise in, and passion for, Computational Chemistry and New Modalities? Would you like to join a world leading team that push the boundaries of science and technology to deliver life-changing medicines? Join us to be part of the discovery of future treatments for Cardiovascular, Renal and Metabolic diseases
AstraZeneca is now recruiting an experienced Computational Chemist to join the Medicinal Chemistry Department within the Cardiovascular, Renal and Metabolism (CVRM) therapeutic area. The position is placed at AstraZenecas dynamic R&D site in the lovely city of Gothenburg, Sweden.
Cardiovascular, Renal and Metabolism (CVRM) is one of AstraZeneca 's core therapy areas. We follow the science and turn ideas into life changing medicines for patients suffering from Heart Failure, Diabetes or Chronic Kidney Disease. To realize our ambitions, we stay agnostic to molecular modality. The Medicinal Chemistry Department within CVRM is a critical player in the discovery and design of our drug molecules and in identifying and validating novel biological targets.
Main Duties and Responsibilities
As a Computational Chemist you will have a profound impact on multiple projects across the CVRM portfolio with a focus on New Modalities such as peptides, PROTACs, and oligonucleotides. You will have a key role in modelling, analysis of large datasets, drug design and you will be a significant contributor to project progression. You will also be involved in building and drive our future design capabilities in the New Modality space. As part of our fast-paced, highly-skilled CVRM computational chemistry team you will operate in a highly cross disciplinary environment in close collaboration with scientists from the Chemistry, Bioscience, DMPK and Pharmaceutical Sciences departments.
* You will simultaneously impact multiple discovery projects by efficiently and pro-actively applying a wide variety of computer-aided drug design approaches
* With your excellent knowledge of modern computational chemistry you will identify and drive our New Modalities in silico capabilities
* You will be expected to plan, write and publish high quality scientific papers
Essential requirements
We are looking for a drug hunter with a PhD (or equivalent experience) in computational chemistry with industry experience from drug design, biophysics, or a related field. You have a high degree of independence and a proven record of excellence in a number of computer-aided drug design techniques to assist in target identification and advancement of discovery programs. In addition you will have:
* Solid knowledge of computer-aided drug design and modern medicinal chemistry.
* Expertise in using standard computational chemistry software.
* Experience of computational chemistry applied to new modalities (e.g. peptides, PROTACs or oligonucleotides).
* Expertise in biophysics, structural modeling and methods to study protein dynamics.
* Knowledge in scientific computing, and programming skills (e.g. Python) is an advantage.
* Expertise in machine-learning methods is a plus.
* Excellent English and ability to communicate both verbally and in writing is required.
At AstraZeneca you will fit right in if you thrive on team work in a multidisciplinary environment, and the ability to influence both people and science.
We would like to know more about you. If you are interested to know more about us, apply now!
For more information about the position please contact recruiting manager Dr. Anders Hogner,
Welcome with your application no later than January 10, 2020.
Additional information
Our Gothenburg site:
https://www.astrazeneca.com/our-science/gothenburg.htmlCulture and atmosphere of the site:
https://www.linkedin.com/feed/update/urn:li:activity:6496327311678410752/Life in Gothenburg and Sweden:
https://www.movetogothenburg.com/AstraZeneca is acting as an Employment Agency in relation to this vacancy.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2019-12-01ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2019-12-29
Klicka på denna länk för att göra din ansökanFöretagAstrazeneca AB
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-067123".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Jobbnummer 4981028
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