Clinical Pharmacometrician In Cvrm

AstraZeneca AB / Biomedicinjobb / Göteborg
2022-05-19
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Do you have expertise and experience in PK and PKPD, mathematical/statistical modelling and simulation, Model Informed Drug Development (MIDD) and its application in drug development? Would you like to apply your knowledge in a company that is following the science and turn ideas into life changing medicines? Then this might be your next challenge!

We now have an exciting opportunity for an engaged and diligent individual to join our growing Clinical Pharmacology and Quantitative Pharmacology (CPQP) team at AstraZeneca at our vibrant Gothenburg site in Sweden, as a Senior Scientist, Associate Director or Director depending on your background, experience and skills.

This is a global role that will support large- and small molecule projects across all phases of clinical development within the therapy area of Cardiovascular, Renal and Metabolism.

Within the Clinical Pharmacology and Safety Sciences (CPSS) function at AstraZeneca, we have a state-of-the-art Clinical Pharmacology and Quantitative Pharmacology (CPQP) organization with a diverse and uniquely skilled team of clinical pharmacometricians and clinical pharmacology scientists. You will thrive in an environment that inspires innovation, encourages multidisciplinary team-working and collaboration with academia, and rewards original scientific thinking.

What you will do
Working closely with clinical pharmacologists, physicians, statisticians and other scientists, you will apply model informed drug development (MIDD) to contribute to clinical programs, to support the design and interpretation of clinical studies and influence key decisions in early and late clinical development.

The work includes integration of relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. Use of simulations and pharmacometric/statistical analyses to inform trial and program designs and decisions are important focus areas for us.

In collaboration with clinical pharmacologists, you will represent CPQP in cross-functional clinical project teams and be responsible for identifying and executing model informed drug development opportunities, to accelerate and inform decision making. Based on your interest, skills and experience, you might also take on strategic planning and delivery of the clinical pharmacology strategy acting as a dual Clinical Pharmacometrician/Clinical Pharmacologist. You will communicate your findings within and outside of AstraZeneca and publish in peer reviewed journals.

Minimum requirements for the role

* PhD or equivalent (M.Sc. or Pharm.D.) in pharmacometrics or mathematical/statistical modeling and simulation or other relevant area
* Strong technical knowledge and hands-on skills in modeling and simulation
* Biological understanding of disease and drug action
* Good oral and written communication skills

Desirable in the role

* 3+ years of industry experience or equivalent in quantitative modelling and its application in drug development
* Track record in creating and delivering on MIDD strategies in clinical drug development programs for both small and large molecules
* Early and late phase clinical development experience
* Understanding of clinical pharmacology aspects of drug development, preferably in both a small and large molecule setting
* Recognized scientific expertise demonstrated by scientific publishing in the field of clinical pharmacology

We truly believe that everyone contributes with a unique set of competence. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximise your skills, abilities and contribution. You have a real passion for your subject, along with a collaborative nature and ability to work in multi-disciplinary global teams.

Why AstraZeneca?
We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide. Collaborate in an inclusive environment, a place full of bold new opportunities. Be empowered to be innovative and creative where difference is valued.

So, what's next? If the sounds like the job and place for you - apply today!

We look forward to find out more about you. Send in your application as soon as possible, we will review applications continuously.

For more information about the position please contact the hiring managers, Angelica Quartino (https://www.linkedin.com/in/angelica-quartino-352a7b2/) or Ann-Charlotte Egnell (https://www.linkedin.com/in/lotta-egnell-9595b0a/)

Where can I find out more?
Our Gothenburg site: https://www.astrazeneca.com/our-science/gothenburg.html
Life in Gothenburg site: https://www.astrazeneca.se/om-oss/verksamheten-i-sverige/goteborg/relocate-to-gothenburg.html
Read more about BioPharmaceuticals R&D: https://www.astrazeneca.com/r-d.html
Follow AstraZeneca on LinkedIn: https://www.linkedin.com/company/1603/

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Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2022-05-19

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2022-06-16
Klicka på denna länk för att göra din ansökan

Företag
Astrazeneca AB

Arbetsgivarens referens
Arbetsgivarens referens för detta jobb är "R-138810".

Omfattning
Detta är ett heltidsjobb.

Arbetsgivare
Astrazeneca AB (org.nr 556011-7482)

Arbetsplats
AstraZeneca

Jobbnummer
6663836

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