Bioanalytical Scientist

AstraZeneca Göteborg / Biomedicinjobb / Mölndal
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We lead our industry in our development of a strong and varied pipeline. This means our people are here to win. We give you a breadth of opportunities to be curious and do cutting edge, unique work that has big impact on science and medicine.

Now we are looking for a bioanalytical scientist with in depth knowledge in the area of quantitative bioanalysis of drugs and drug metabolites to join our team in the Cardiovascular & Metabolic Diseases Innovative Medicines Unit (CVMD iMed) DMPK department.

CVMD iMed is based in AstraZeneca?s world-class vibrant R&D center, located in Gothenburg, Sweden. CVMD iMed DMPK interacts with other functions in supporting CVMD projects all along the value chain, from target selection all the way to market launch and Life cycle management.

Main Duties and Responsibilities

You will be responsible for analysing drug candidates and their metabolites in various in vitro and in vivo samples including sub-cellular fractions as well as tissues, plasma and bile samples.

The team you will be part of is focusing on metabolism, biodistribution and disposition of small molecule, conjugated peptide and nucleotide drug candidates. You will have the opportunity to contribute to the discovery of new life changing medicines for patients and demonstrate and witness what science can do.

Your responsibility will include delivering quality in vitro and in vivo bioanalytical data including analysis of drugs, drug candidates and drug metabolites in various in vitro and in vivo samples including cells, sub-cellular fractions, tissues, plasma, and bile samples to support PKPD (Pharmacokinetics and Pharmacodynamics) and biotransformation work in projects from target selection to LCM (life cycle management). The data generated is mainly aimed to provide insight to quantitative pharmacology as well as to right tissue and right exposure aspects including the fates of drug molecules/metabolites.

This laboratory based scientific role includes developing and validating methods to enable delivery of data with the necessary quality and scientific information aligned with the project needs. The role requires interactive, effective communication to provide clear data and guidance to project representatives, act as an example to other scientists, and contribute to the overall team delivery. It will also require making judgements about bioanalysis information, developing innovative solutions and applying cross-disciplinary understanding.

Essential requirements
B.Sc or equivalent degree in a relevant discipline
Track record of delivering state-of-the-art bioanalysis data to projects in discovery and/or development setting
Good knowledge of liquid chromatography and mass spectrometry ionization and detection (LC-MS/MS) and bioanalytical work in Drug Discovery & Development
Good knowledge of bioanalysis of peptides and oligonucleotides
Basic understanding of DMPK
Experience with in vitro incubations is a plus.
Understanding of the overall drug discovery and development process.
Good oral and written communication skills in English.

Welcome with your application no later than November 8th, 2016.

Varaktighet, arbetstid
Tillsvidare
Heltid

Publiceringsdatum
2016-10-11

Ersättning
Fast månads- vecko- eller timlön

Så ansöker du
Sista dag att ansöka är 2016-11-08
Ange följande referens när du ansöker: R-000379

Företag
AstraZeneca Göteborg

Adress
AstraZeneca Göteborg
43183 MÖLNDAL

Kontorsadress
PEPPAREDSLEDEN 1
MÖLNDAL

Övriga kontaktuppgifter
Telefonnummer: 031-7761000

Jobbnummer
3098931

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Bioanalytical Scientist

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