Bioanalysis Scientist Dmpk To Astrazeneca Gothenburg
Alten Sverige AB / Biomedicinjobb / Göteborg
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hela Sverige About AstraZeneca
AstraZeneca is a global, innovation-driven biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world's most serious diseases. In addition to being one of the world's leading pharmaceutical companies, AstraZeneca is proud to provide a unique workplace culture that inspires innovation and cross-boundary collaboration. Within this environment employees are empowered to express diverse perspectives, and are made to feel valued, energized and rewarded for their ideas and creativity.
The Arena:
Early Research and Development Cardiovascular, Renal and Metabolism (Early CVRM) is one of the main therapeutic research areas within BioPharmaceuticals R&D which deliver candidate drugs into late-stage clinical development. This role in Early CVRM is based in AstraZeneca's world-class vibrant R&D center, located in Gothenburg, Sweden. Early CVRM DMPK interacts with other functions in supporting CVRM projects all along the value chain, from target selection all the way to market launch and Life cycle management.
Now we are looking for a bioanalytical scientist with good knowledge in the area of quantitative bioanalysis of drugs and drug metabolites to join our team in the DMPK department for a consultant assignment. The team you will be part of is focusing on pharmacokinetics, biodistribution and disposition of small molecule, conjugated peptide and nucleotide drug candidates. You will have the opportunity to contribute to the discovery of new life changing medicines for patients and demonstrate and witness what science can do.
Tasks and responsibilities:
You will be responsible for analysing drug candidates and their metabolites in various in vitro and in vivo samples including plasma, tissue, and bile samples as well as sub-cellular fractions.
Your responsibility will include delivering quality in vitro and in vivo bioanalytical data including analysis of drugs, drug candidates and drug metabolites in various in vitro and in vivo samples to support PKPD (Pharmacokinetics and Pharmacodynamics) work in projects from target selection to LCM (life cycle management). The data generated is mainly aimed to provide insight to quantitative pharmacology as well as to right tissue and right exposure aspects, including the fates of drugs and their metabolites.
This laboratory based scientific role includes developing and validating methods to enable delivery of data with the necessary quality and scientific information aligned with the project needs. The role requires interactive, effective communication to provide clear data and guidance to project representatives, act as an example to other scientists, and contribute to the overall team delivery. It will require making judgements about bioanalysis information, developing innovative solutions and applying cross-disciplinary understanding.
Minimum requirements and key factors:
• M.Sc or equivalent degree in a relevant discipline is required (e.g analytical chemistry, biochemistry, biotechnology or pharmacy)
• Good knowledge of liquid chromatography and mass spectrometry ionization and detection (LC-MS/MS) and bioanalytical work in Drug Discovery & Development
• Track record of delivering state-of-the-art bioanalysis data to projects in discovery and/or development setting is a clear advantage
• Basic understanding of DMPK
• Understanding of the overall drug discovery and development process
• Good communication skills in English, both verbal and in writing are required
• Demonstrated ability to work in team and independently
What we offer you at ALTEN
Every employee is equally valuable in the success of ALTEN! We are driven by making people grow and develop, which is why we offer you the opportunity to work with what you are truly passionate about. At ALTEN, we have a broad range of assignments at most of the leading companies in Sweden in several different sectors, to make it possible for your wishes to come true. We offer both national and international opportunities and together with your coaching manager, you build your career path so you constantly are able to develop and achieve your goals and dreams!
As a consultant at ALTEN, you will get the genuine team feeling at your assignment but also a wonderful togetherness at ALTEN. Through our different internal networks, such as ALTEN Sports, Women@ALTEN and ALTEN Innovation you will get the opportunity to drive topics and activities that are close to your heart, together with your colleagues. All activities are of course optional. Work life balance is our top priority. We also have a collective agreement and other benefits like Pension, Insurances and Wellness grants.
We believe in growing together!
Varaktighet, arbetstid
Heltid Tillsvidareanställning
Publiceringsdatum2019-11-28ErsättningEnligt överenskommelse
Så ansöker duSista dag att ansöka är 2019-12-06
Klicka på denna länk för att göra din ansökanFöretagAlten Sverige AB
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Alten Sverige AB (org.nr 556420-7453)
Jobbnummer 4967687
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