Associate Principal Scientist, Translational Genomics
AstraZeneca / Biologjobb / Göteborg
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The Discovery Sciences, Translational Genomics department is looking for an Associate Principal Scientist to be part of our in vivo physiology discipline within the Transgenic Models team. This position is based at the AstraZeneca R&D site in Gothenburg, Sweden and we are seeking a scientific and technical specialist in the animal in vivo physiology field.
Main Duties and Responsibilities
The Associate Principal Scientist role is experimentally focused with strong troubleshooting skills, adept at putting ideas into practice and providing support, supervision and coaching to more junior scientists. You will represent the department at internal interdisciplinary meetings in addition to external meetings and publish novel science in impactful journals. You will also propose experimental strategies and make significant contributions to the practical delivery of projects in compliance with AstraZeneca corporate responsibility policies and relevant safety standards and of central importance is experience with murine in vivo experimentation.
Specific responsibilities
* Develop and drive the in vivo physiology discipline with full engagement with stakeholders to ensure the discipline operates at the scientific forefront, using world leading technologies and infrastructure to support all core disease areas
* Lead projects and studies and ensure that they are conducted with quality, dedication and data delivered according to stipulated time lines and project requirements
* Point of contact for other global AstraZeneca in vivo departments globally
* Compile, interpret, present and discuss data with key project teams and stakeholders
* Actively promote the in vivo physiology discipline activities to ensure visibility in the wider AstraZeneca organization
* Hands on activity in the lab when required for timely project progression
* As a senior researcher you will be a mentor for more junior scientists through advising, challenging and by providing expert advice to aid interpretation of complex data.
Essential Requirements
You should have a Ph.D. degree or corresponding experience in a relevant scientific discipline with experience in drug discovery or, alternatively, a first degree and significant relevant experience in drug discovery. You should have good social and communication skills, be collaborative and be a strong team player. Furthermore, you should be able to work independently and have a positive, goal oriented and problem-solving attitude. Good organisational skills are required and you should be comfortable in presenting your results. Excellent English is required, both spoken and written.
* Experience in metabolic phenotyping platforms and analysis of metabolic function in mouse models e.g. performing indirect calorimetry and intraperitoneal glucose tolerance tests (IPGTT) to diagnose metabolic function in genetically-engineered mice, phenotyping platforms such as hyperinsulinemic-euglycemic clamps.
* Molecular biology expertise and a working knowledge of the latest precise genome engineering tools both in vitro and in vivo.
* Expertise in the generation and characterization of transgenic animal models
* Generation and use of viral vectors for in vivo genetic engineering
For more information about the position please contact Mohammad Bohlooly at +46 31 706 4181 or
Welcome with your application no later than January 1st 2019.
For more information about life in Gothenburg visit
www.movetogothenburg.comOur stunning campus in Gothenburg is one of AstraZeneca's three strategic science centres. The site is home to over 2,500 employees, from 50 different nationalities. Gothenburg includes the complete range of functions, and as such offers plenty of development opportunities for a wide range of professionals. Our science teams in Gothenburg collaborate with academic and industry partners in Sweden and globally. And the site itself has been designed with collaboration in mind. From the Coffee Lab to exercise areas, we've created a series of environments where innovation can happen.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-11-27ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-12-25
Ange följande referens när du ansöker: R-030235
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
karin.lyckemalm@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparredsleden 1
Jobbnummer 4481677
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