Passionate Senior Clinical Pharmacometrician to Gothenburg
AstraZeneca AB / Biomedicinjobb / Göteborg
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hela Sverige Do you have great expertise and experience in mathematical/statistical modelling and simulation, PKPD and its application in drug development? Would you like to apply your knowledge in a company that is following the science and turn ideas into life changing medicines? Then this might be your next challenge!
This is an opportunity for a hardworking and engaged individual to join our growing Clinical Pharmacology and Quantitative Pharmacology (CPQP) team at AstraZeneca in Gothenburg (Sweden) and contribute as a Senior Clinical Pharmacometrician supporting large and small molecule projects across all phases of clinical drug development within the therapy area of Cardiovascular, Renal and Metabolism.
In this role you will be a part of the Clinical Pharmacology and Safety Sciences (CPSS) function. Within CPSS, we have a state-of-the-art quantitative CPQP organization with a diverse and uniquely skilled team of clinical pharmacometricians, clinical pharmacology scientists and other specialists. You will thrive in an environment that inspires innovation, encourages multidisciplinary team-working and collaboration with academia, and rewards original scientific thinking.
What you will do:
Working closely with clinical pharmacology scientists, physicians and other scientists, you will apply model informed drug development (MIDD) to contribute to the clinical program, to support the design and interpretation of clinical studies and influence key decisions in early and late clinical development.
As a Senior Clinical Pharmacometrician you will work hands-on with clinical data to integrate relevant data, such as dose information, pharmacokinetics, biomarkers and clinical endpoints within and across studies, compounds and development stages. It also involves disease and translational modeling. Use of simulations and informative pharmacometric/statistical analyses to inform trial and program designs and decisions are important focus areas for us.
In collaboration with clinical pharmacology scientists, you will represent CPQP in cross-functional clinical project teams and be responsible for identifying and executing model informed drug development to accelerate and inform decision making. You will communicate your findings within and outside of AstraZeneca and publish in peer reviewed journals.
Essential in the role:
* PhD or equivalent (M.Sc. or Pharm.D.) with at least 3-5 years' experience in quantitative modelling , e.g. knowledge in mathematics and statistics applied to life sciences.
* Experience in combined industry and/or Regulatory postdoctorial experience in the field of quantitative modelling.
* Strong background in, and an understanding of clinical pharmacology aspects of drug development, preferably in both a small and large molecule setting.
* Good knowledge of pharmacokinetics, PKPD and its clinical applications.
* Biological understanding of disease and drug action.
Desirable in the role:
* Track record in creating and delivering on MIDD strategies in clinical drug development programs for both small and large molecules.
* Recognized scientific expertise demonstrated by scientific publishing in the field of clinical pharmacology.
* Early or late phase clinical development experience.
We truly believe that everyone contributes with a unique set of competence. Your curiosity and passion for personal development combined with support from colleagues, mentors and leaders, will ensure you maximise your skills, abilities and contribution. You have a real passion for your subject, along with a collaborative nature and ability to work in multi-disciplinary global teams.
Why AstraZeneca?
We are a global, science-led BioPharmaceutical business and our innovative medicines are used by millions of patients worldwide. Collaborate in an inclusive environment, a place full of bold new opportunities. Be empowered to be innovative and creative where difference is valued.
So, what's next? If the sounds like the job and place for you - apply today!
We look forward to find out more about you. Send in your application as soon as possible, but no later than 23rd May, 2021.
For more information about the position please contact the recruiting manager, Susanne Johansson (+46708467521 ).
Additional information:
Our Gothenburg site:
https://www.astrazeneca.com/our-science/gothenburg.htmlLife in Gothenburg:
https://www.movetogothenburg.com/About BioPharmaceuticals R&D:
https://www.astrazeneca.com/r-d.htmlVaraktighet, arbetstid
Heltid Permanent
Publiceringsdatum2021-04-23ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2021-05-07
Klicka på denna länk för att göra din ansökanFöretagAstrazeneca AB
Arbetsgivarens referens Arbetsgivarens referens för detta jobb är "R-106408".
Omfattning Detta är ett heltidsjobb.
Arbetsgivare Astrazeneca AB (org.nr 556011-7482)
Arbetsplats AstraZeneca
Jobbnummer 5715257
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