Senior Research Scientist Genome Editing
Poolia Göteborg AB / Apotekarjobb / Göteborg
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hela Sverige AstraZeneca are now looking for a talented and motivated Senior Research Scientist within Genome Editing. You will be embedded in an international group working on cutting edge technologies with world leading external collaborators. The consulting assignment will start 2018-05-02 and go on to 2018-09-30.
about the consultant assignment
The Arena:
The precise genome editing group is developing new tools and technologies to facilitate target validation, speedy disease modeling and to evaluate the potential applications and safety of therapeutic genome editing. We are part of the Translational Genomics department where we develop advanced cellular and animal models and we also provide expert support for Next Generation Sequencing and Transcriptome analysis. The candidate will be embedded in an international group working on cutting edge technologies with world leading external collaborators.
Tasks and responsibilities/The role:
• To design and build genome editing-based strategies and tools required to generate in vivo (mouse) and in vitro reagents to create disease models
• To develop delivery tools to improve the efficiency of in vivo genome editing
• To perform confirmation of genetic manipulation and functional validation of engineered animals
• To perform target validation studies in early projects
Who you are
Minimum requirements:
• Molecular biology expertise on vector design and genetic manipulation of cell lines and/or mouse embryonic stem cells, primary and iPSC cells
• Functional characterization of gene modified cell lines
• In silico construct design and analysis of genetic perturbation after genome editing
Preferred experience and key factors:
• Generation and use of viral vectors (lentivirus, AAV, Adenovirus) and non-viral delivery tools for in vitro and in vivo delivery
• Previous practical expertise with genome editing tools including Cas9/CRISPR, ZFNs and TALENs
• Hands on experience with Next Generation Sequencing library preparation and results analysis
About Poolia & AstraZeneca
Poolia take good care of our consultants and we offer social activities, as well as help in planning your future career. Your consultant manager is well experienced from your field, and knows how to get the most out of your assignment. As a Poolia employee, you are included in the requirements concerning agreements on terms of employment by Unionen. Moreover, you get a grant for working out at your choice of place. You are also covered by a health Insurance.
AstraZeneca (AZ) is a major international healthcare business engaged in the research, development, manufacture and marketing of prescription pharmaceuticals and the supply of healthcare services. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.
Next step, apply today!
Varaktighet, arbetstid
Heltid Sex månader eller mera
Publiceringsdatum2018-04-09ErsättningFast månads- vecko- eller timlön
Så ansöker duSista dag att ansöka är 2018-04-16
Ange följande referens när du ansöker: 50027
Klicka på denna länk för att göra din ansökanFöretagPoolia Göteborg AB
AdressPoolia Göteborg AB
Kungsgatan 42
41115 Göteborg
KontorsadressKungsgatan 42
Jobbnummer 4071432
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