Modelling tools for high shear wet granulation
Chalmers tekniska högskola / Kemistjobb / Göteborg
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Chalmers is a university of technology in which research and teaching are conducted on a broad front within technology, natural science and architecture. Currently there are approximately 11 000 students and 2400 employees at Chalmers.
The division of Chemical Engineering at Department of Chemical and Biological Engineering at Chalmers University of Technology has a staff of around 35 people. The main research areas are: multi-phase flows in chemical engineering; particulate processes; transport phenomena and mathematical modelling.
The project is part of a larger project, PowTech, funded by EU. PowTech is an Initial Training Network (ITN) aiming to integrate inter-sectoral and multidisciplinary research in particle and powder technology into the training of 15 highly skilled young researchers, to strengthen the competitiveness of food and pharmaceutical industry and to strengthen the European Research Area. The people and the knowledge in powder technology to be developed in the PowTech network will contribute to the development of innovative products and effective powder processing in Europe by solving industrial problems and reducing knowledge barriers.
We are looking for 15 Early Stage Researchers (ESRs) to be employed within PowTech ITN during a three years period. The candidates will perform doctoral research sharing their time between main host and a secondment location (approx 6 months, generally an industry). During this period, they will also have the opportunity to attend several training courses that will be hold within the PowTech Graduate School.
Job description
The over-all goal of the present project is to develop mathematical models for high-shear wet granulation to be used for design, scale-up, operation, control and optimization of tabletting formulations in high-shear mixers. This is of high relevance for the pharmaceutical industry and requires a coupling between models at the particle level (population balances) with models for the flow- and shear-fields. The models will be experimentally verified.
Specifically, experimental and theoretical methods to describe multi-dimensional evolution of agglomerates using population balances; flow in dense particle systems; and coupling between flow and population balance models, will be developed. The project is a joint venture between AstraZeneca Mölndal and Chemical Engineering at Chalmers.
Previous work by the research group has been focused on development and validation of population balances (Niklasson Björn et al, 2005; Darelius et al, 2005; 2006), but initial experimental (Darelius et al, 2007a;b) and modelling (Darelius et al, 2008; 2010) work at the macroscopic flow level has also been performed.
Required qualifications
A suitable background is Master of Science (Swedish: civilingenjör) in Chemical engineering, Mechanical Engineering or Engineering Physics; specifically with interest in applied mathematics and transport phenomena.
Applicants can be nationals of any country other than the country of the premises of the host organization where the project is carried out. At the time of appointment, the applicant may not have resided or carried out the main activity in the country of the host for more than 12 months in the 3 years immediately prior to the recruitment.
Publiceringsdatum2011-04-12Arbetstider och omfattningVisstidsanställning 6 månader eller längre
Heltid
ErsättningFast lön
Så ansöker duSista dag att ansöka är 2011-05-06
Ansökan sker via företagets webbplats.
Ange följande referens när du ansöker: REF 2011/99
Ansökan kan tyvärr inte göras via e-post.
KontaktIngela Björn, Pharmaceutical Development, AstraZeneca R&D, +46 31 776 2179,
Ingela.Niklasson-Bjorn@astrazeneca.comAnders Rasmuson, Professor, +46 31-772 29 40,
rasmuson@chalmers.seFacklig kontaktJan Linder, SACO, 031-7721000,
jan.linder@chalmers.seMarie Wenander, ST, 031-7721000,
marie.wenander@chalmers.seJohan Persson, SEKO, 031-7721000,
johan.persson@chalmers.seFöretagChalmers tekniska högskola
AdressChalmers tekniska högskola
41296 GÖTEBORG
KontaktuppgifterTelefonnummer: 031-772 10 00
Jobbnummer 902508
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