Biopharmaceutics Modelling and Simulation expert
AstraZeneca / Apotekarjobb / Göteborg
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hela Sverige Are you an expert in biopharmaceutics modelling and simulation with experience in developing and implementing models within the area Biopharmaceuticals? Would you like to apply your expertise in a company that are following the science and turn ideas into life changing medicines? Then you might be the one we are looking for!
AstraZeneca is now recruiting an Associate Principal Scientist with expertise in Biopharmaceutics Modelling and Simulation to join the Early Product Development (EPD) function within Pharmaceutical Sciences at AstraZeneca. The role focus on physiologically based modelling of inhaled molecules like RNA, oligonucleotides and small proteins and is placed in Gothenburg (Sweden).
Pharmaceutical Sciences is a department within our Innovative Medicines and Early Development (IMED) Biotech unit. The Pharmaceutical Sciences' mission is to transform molecules into investigational medicines, meeting the unmet needs of future patients. Our portfolio of projects spans traditional small molecules, proteins, oligonucleotides to RNA based therapeutics across AstraZeneca's therapy areas. Pharmaceutical Science at AstraZeneca is aiming to strengthen the modelling and simulation capability. The EPD group is a multidisciplinary function comprising formulation, analytical, biopharmaceutics, solid state and predictive sciences. We provide input into compound design & selection, as well as design and development of formulations from discovery up to and including Phase II clinical studies.
Main Duties and Responsibilities
In this role, you will work across all the Global Pharmaceutical Sciences departments along with other senior scientists to provide scientific leadership and drive innovation. You will be responsible for developing and apply modelling approaches to identify opportunities and address challenges in developing of compounds and products in alignment with the overall Pharmaceutical Sciences strategy. Specific responsibilities include:
* Deliver high quality modelling to drug projects and scientific excellence in the discipline in particular at compound selection for candidate drugs and early development
* Represent Pharmaceutical Sciences modelling and simulation externally to drive scientific excellence and AstraZeneca's reputation in the field
* Identify and explore new opportunities for computational support to the drug discovery and development process
* Identify opportunities for external scientific collaborations and lead collaboration projects
* Develop, validate and implement modelling protocols to be used by general users
* Work across disciplines and skill groups within and outside Pharmaceutical Sciences
* Act as a role model and mentor to scientists with less experience in modelling and simulation
* Develop training material and provide training to user groups
* Drive innovation in the modelling and simulation arena
Requirements
* PhD in a relevant area e.g. biopharmaceutics modelling, physical chemistry, biophysics, mathematical and statistical modelling, typically with +5 years post-doctoral experience
* Excellent awareness of recent literature within field of expertise
* Good knowledge of programming and scripting
* Good understanding of pharmaceutical R&D and the wider business
* God knowledge of all disciplines within early product development and drug discovery
* Good track record of professional achievement and recognition in own field
* Experience from leading scientific collaboration between industry and academia
* Able to think beyond boundaries of own job, challenging status quo and seeking opportunities for business improvement
* Capable of making effective decisions, acting courageously and communicating with conviction and inspiration at all levels
* Excellent team working, networking and influencing skills
* Excellent communication skills
Specific technical requirements
* Experience from modelling tools like Matlab, Gastroplus, Simcyp, Berkeley Madonna
* Programming: visual basic/visual C, Fortran
* Desirable: Knowledge of inhaled drug delivery, respiratory diseases and new modalities
If you are interested, apply now!
For more information please contact recruiting manager Anders Broo, PhD on +46 722 108177
Welcome with your application no later than April 8 , 2018.
AstraZeneca is a global, science-driven biopharmaceutical company. We turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. Here, we see the impact of our collective ideas and expertise, and the power of science to deliver them.
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law.
Varaktighet, arbetstid
Heltid Permanent
Publiceringsdatum2018-03-28ErsättningNot Specified
Så ansöker duSista dag att ansöka är 2018-04-07
Ange följande referens när du ansöker: R-024180
Klicka på denna länk för att göra din ansökanKontaktAstraZeneca
ulrica.marklund1@astrazeneca.comFöretagAstraZeneca
AdressAstraZeneca
43183
43183 1480
KontorsadressPepparedsleden 1
Jobbnummer 4050196
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