Associate Principal Pathologist, Drug Safety & Metabolism

AstraZeneca / Läkarjobb / Göteborg
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At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We're focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life.

Each and every one of us believes that science has the ability to change lives and that to deliver this takes many people with many skill sets. When we deliver a life-changing medicine, that success comes from the combined efforts of all of our people.

As a Pathologist in the Drug Safety and Metabolism department of AstraZeneca's Innovative Medicine & Early Development (IMED) unit, you will be helping to take new targets and molecules all the way from idea to licensing and beyond, supporting translational questions, efficacy testing, patient safety and regulatory requirements. You will be joining an outstanding global team of Pathologists and will have the opportunity to participate in cutting edge drug development in a multidisciplinary environment with strong collaborative culture.

We are looking for a talented, collaborative and highly motivated pathologist with experience in both experimental and toxicologic pathology to join our team in Gothenburg, Sweden, to support projects in the Cardiovascular and Metabolic Disease (CVMD) area covering diabetes, obesity and liver disease. In this role, a research background in this area including deep understanding of human metabolic disease biology, molecular mechanisms, and knowledge of relevant efficacy models is an important asset.

Main Duties and Responsibilities

As the Pathology expert metabolic diseases, you will be working closely with project leaders and colleagues in Drug Safety & Metabolism on project related issues such as target validation, efficacy testing, and safety risks. You will be expected to support innovation in metabolic disease and first in class treatment opportunities.

In particular, responsibilities will include:

* assessing safety and efficacy of novel compounds;
* contributing to study design, data interpretation and integration;
* evaluating the pathology portion of early safety studies;
* designing and evaluating mechanistic and investigative pathology studies;
* conducting hazard characterisation and risk assessment
* communicating findings and making recommendations to key stakeholders.
* Contributing to in vitro and in vivo disease model validation;
* Supporting Discovery research programs by providing a comparative and translational pathology view to projects, animal models and biomarkers;

Essential Requirements

* Doctor of Medicine/ Veterinary Medicine (MD/ DVM) or equivalent degree
* Residency or other specialty training in anatomic and/or toxicologic pathology
* Ph.D. in an aligned scientific field -Previous pharmaceutical /CRO /experimental pathology experience

Desirable Requirements

* Previous industry experience
* Post graduate pathology qualification/ certification (e.g. ACVP, ECVP, FRCPath)
* Experience in the evaluation of metabolic disease models or a research background with an emphasis on diabetes and liver disease would be an added benefit.

If you are interested, apply now!

For more information about the position please contact Silvia Guionaud at +44 746 9408694

Welcome with your application no later than December 20, 2017.

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ies where the role is advertised.

Varaktighet, arbetstid
Heltid Permanent

Publiceringsdatum
2017-12-06

Ersättning
Not Specified

Så ansöker du
Sista dag att ansöka är 2017-12-20
Ange följande referens när du ansöker: R-006119
Klicka på denna länk för att göra din ansökan

Kontakt
AstraZeneca asa.lothigius@astrazeneca.com

Företag
AstraZeneca

Adress
AstraZeneca
43183
43183 1480

Kontorsadress
Pepparedsleden 1

Jobbnummer
3840030

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